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Displaying results 81 - 90 of 536 in total
  1. Drug

    Cocaine

    go.drugbank.com/drugs/DB00907
    ApprovedIllicitInvestigational

    It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. … Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

  2. Drug

    MMDA

    go.drugbank.com/drugs/DB01442
    ExperimentalIllicit

    MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen.

    Categories: Amphetamines
  3. Pathway

    Galantamine Action Pathway (new, revision)

    smpdb.ca/view/SMP0126671
    Drug action

    Galantamine is a cholinesterase inhibitor used in the treatment of Alzheimer's disease, specifically to mitigate symptoms of mild to moderate dementia. These symptoms of cognitive loss are due to acetylcholine deficiency, galantamine inh...

    Drugs: Choline · Galantamine · Calcium · Magnesium cation · Acetylcholine · Acetic acid
  4. Pathway

    Alendronate Action Pathway (New Revised)

    smpdb.ca/view/SMP0126316
    Drug action

    Alendronate also known as alendronic acid is a bisphosphonate drug that is used to treat osteoporosis by preventing osteoclastic bone resorption. Alendronate is a second-generation bisphosphonate as it contains a nitrogen group that acts...

    Drugs: ATP · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid · Cholesterol +2 more
  5. Drug

    Phenelzine

    go.drugbank.com/drugs/DB00780
    ApprovedInvestigational

    Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA ap...

  6. Drug

    Potassium sodium hydrogen citrate

    go.drugbank.com/drugs/DB16585
    Investigational

    Synonyms: Hexapotassium hexasodium pentacitrate hydrate complex
  7. Drug

    Nacystelyn

    go.drugbank.com/drugs/DB17839
    Experimental

    Synonyms: L-lysine, compd. with n-acetyl-l-cysteine
  8. Pathway

    Mitochondrial Complex II Deficiency

    smpdb.ca/view/SMP0125754
    Disease

    Interestingly, complex II deficiency gene mutation carriers may be at an increased risk for certain cancers. … Because complex II is found in the mitochondria, CII deficiency is technically considered a mitochondrial disease.

    Drugs: Pyruvic acid · Biotin · Succinic acid · NADH · ATP · Magnesium cation +4 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
  9. Drug

    Mephedrone

    go.drugbank.com/drugs/DB13108
    Investigational

    Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.

    Categories: Amphetamines
  10. Drug

    Fencamfamin

    go.drugbank.com/drugs/DB01463
    ApprovedIllicitWithdrawn

    Fencamfamin (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend ...