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Amitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin Receptor AntagonistsProducts: Amitriptyline Hydrochloride Tablets USPThreonine
go.drugbank.com/drugs/DB00156ApprovedInvestigationalNutraceuticalAn essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Mixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseAromatase Deficiency
smpdb.ca/view/SMP0000565DiseaseAromatase deficiency is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of mutations in the CYP19A1 gene. The CYP19A1 gene encodes for the enzyme aromatase. Aromatase converts androgens to estrogens which is vita...
Enzymes: Estradiol 17-beta-dehydrogenase 1Chlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. … One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Mixtures: Up and Up Cold Relief, Up and Up Childrens Multi Symptom Cold Pain Relief PlusProducts: Chlorpheniramine Maleate Injection USPOrnidazole
go.drugbank.com/drugs/DB13026InvestigationalOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Products: PRONİZOL 500 MG/3 ML IV İNFÜZYONLUK ÇÖZELTİ (Bitdazol IV İnfüzyon İçin Çözelti İçeren Ampul 500 mg/3 ml), 1 ADET, ORNIJECT 500 MG/3 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADETPregnancy zone protein
go.drugbank.com/bio_entities/BE0009089TargetHumansIs able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves...
Polypeptides: Pregnancy zone proteinBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigational[L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence is limited and there is inconsistent evidence to suggest its clinical efficacy in managing alcohol … Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients.
Categories: GABA-B Receptor AgonistsProducts: Baclofen Injection USPAmubarvimab
go.drugbank.com/drugs/DB16493InvestigationalAmubarvimab (BRII-196) was under investigation in clinical trials (NCT04691180 and NCT04787211) to treat COVID-19, focusing on its safety, tolerability, and efficacy.
Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) SPIKE (S) GLYCOPROTEIN, RECEPTOR BINDING DOMAIN (RBD)), HOMO SAPIENS MONOCLONAL ANTIBODYWU-CART-007
go.drugbank.com/drugs/DB18617InvestigationalWU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Synonyms: an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7