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Pyronaridine
go.drugbank.com/drugs/DB12975InvestigationalPyronaridine has been investigated for the treatment of Malaria.
Categories: Heterocyclic Compounds, 2-RingBiapenem
go.drugbank.com/drugs/DB13028InvestigationalIt is a carbapenem antibiotic with a methyl group on the 1-beta position, which gives it stability against degradation by dehydropeptidase I.[A275008]
Categories: Heterocyclic Compounds, 2-RingTramazoline
go.drugbank.com/drugs/DB13064InvestigationalTramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).
Categories: Heterocyclic Compounds, 1-RingMacimorelin
go.drugbank.com/drugs/DB13074ApprovedThe diagnosis of AGHD requires biochemical confirmation with at least 1 GH stimulation test [A31481]. … Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis of adult GH deficiency (AGHD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesZidebactam
go.drugbank.com/drugs/DB13090ApprovedZidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2. … [L63350] It is available only in fixed combination with [cefepime], which binds PBP3 and PBP1a/b.
Categories: Heterocyclic Compounds, 1-RingPlecanatide
go.drugbank.com/drugs/DB13170ApprovedInvestigationalPlecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC).
Categories: Guanylate Cyclase-C Agonist, Guanylyl Cyclase C AgonistsGluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalCommonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Synonyms: D-Gluconic AcidMixtures: Normosol-R & 5% Dextrose, Isolyte S With 5% Dextrose InjSodium chlorite
go.drugbank.com/drugs/DB13210InvestigationalFood and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].
Products: Qve - S, V Doctor pure chlorine dioxideTuaminoheptane
go.drugbank.com/drugs/DB13238ExperimentalTuaminoheptane is a sympathomimetic drug typically used as a nasal decongestant.[A198534,A275018]
Synonyms: 2-Heptanamine, 2-Aminoheptane