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Displaying results 901 - 910 of 10000 in total
  1. Target

    Ephrin type-A receptor 8

    go.drugbank.com/bio_entities/BE0009440
    TargetHumans

    During development of the nervous system also plays a role in axon guidance. … The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation.

    Polypeptides: Ephrin type-A receptor 8
  2. Target

    Neutral amino acid transporter A

    go.drugbank.com/bio_entities/BE0000480
    TargetHumans

    Involved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. … Displays sodium- and amino acid-dependent but uncoupled channel-like anion conductance with a preference SCN(-) > NO3(-) > I(-) > Cl(-) (PubMed:8910405)

    Polypeptides: Neutral amino acid transporter A
  3. Target

    U1 small nuclear ribonucleoprotein A

    go.drugbank.com/bio_entities/BE0002708
    TargetHumans

    In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs

    Polypeptides: U1 small nuclear ribonucleoprotein ASynonyms: U1-A, U1 snRNP A
  4. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0003726
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  5. Target

    Myocardin-related transcription factor A

    go.drugbank.com/bio_entities/BE0004156
    TargetHumans

    Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:26224645). The SR...

    Polypeptides: Myocardin-related transcription factor ASynonyms: MRTF-A
  6. Target

    Ephrin type-A receptor 5

    go.drugbank.com/bio_entities/BE0005587
    TargetHumans

    Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. … Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis.

    Polypeptides: Ephrin type-A receptor 5
  7. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    In the nervous system, also plays a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. … In addition to its role in axonal guidance plays a role in synaptic plasticity.

    Polypeptides: Ephrin type-A receptor 4
  8. Target

    Acyl-coenzyme A thioesterase 1

    go.drugbank.com/bio_entities/BE0016368
    EnzymeHumans

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.

    Polypeptides: Acyl-coenzyme A thioesterase 1Synonyms: Palmitoyl-coenzyme A thioesterase, Inducible cytosolic acyl-coenzyme A thioester hydrolase
  9. Drug

    Mineral oil

    go.drugbank.com/drugs/DB11057
    ApprovedInvestigationalVet approved

    Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. … It is also used as a mild laxative for human or veterinary uses.

    Mixtures: AGAROL CON SABOR A FRAMBUESA, Rx Act HemorrhoidalProducts: Truffle EX Cleansing, Gelee Laxative A LA Framboise
  10. Drug

    Ibandronate

    go.drugbank.com/drugs/DB00710
    ApprovedInvestigational

    [L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.[A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805] … Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].

    Mixtures: IBONE D®, IBONE D 30000Products: IBANDRONSAEURE AL 3 MG FER, BONVIVA 3MG/3ML FER