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Prednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approved[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496] … A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.
Categories: CHOP-R chemotherapy regimen, P-glycoprotein inducersSynonyms: 1, 2-Dehydrocortisone, 1,4-Pregnadiene-17α,21-diol-3,11,20-trioneOndansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawn[L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has demonstrated a long history of use and efficacy.
Categories: Serotonin 5-HT3 Receptor Antagonists, Antiemetic Serotonin 5-HT3 Receptor AntagonistsProducts: ZOPHRALEN 4 MG/2 ML IV AMPUL, 5 ADET, LAUFRAN 4 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETStavudine
go.drugbank.com/drugs/DB00649ApprovedInvestigationalA dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Mixtures: TRIVIRO LNS® LAMIVUDINA 150 MG NEVIRAPINA 200 MG ESTAVUDINA 40 MG, TRESLAM ® 30Categories: Heterocyclic Compounds, 1-Ring, Antivirals used in combination for the treatment of HIV infectionsExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalExenatide was given FDA approval on April 28, 2005[L6106]. It is available as immediate- and extended-release formulations. … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690].
Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analoguesSynonyms: Exendin 4, Exendin-4Flurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Mixtures: KLORHEX PLUS 2.5 MG/ML + 1.2 MG/ML ORAL SPREY, ÇÖZELTİ, 30 ML, KLORHEX PLUS 2.5 MG/ML + 1.2 MG/ML GARGARA,200 MLCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesDoxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigationalDoxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. … [A180661] Because of its long-lasting effects, doxazosin can be administered once a day.[A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285]
Synonyms: 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin, 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazinInternational brands: Cardura-2, Cardura-1Prednicarbate
go.drugbank.com/drugs/DB01130ApprovedIt has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a low potential to cause skin atrophy. … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness.
Mixtures: SKINPRED® ULTRACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigationalMerck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and … [A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingProducts: ACETUDIL FORTE 60 MG KAPSÜL, 20 ADET, RANTUDIL FORTE 60 MG KAPSUL, 20 ADETFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular … [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acidPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Mixtures: Cremo All-Season Lip Balm SPF 25 Vanilla Mint, Chapstick 12 Days of ChristmasCategories: Compounds used in a research, industrial, or household setting