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House dust
go.drugbank.com/drugs/DB10345ApprovedHouse dust allergenic extract is used in allergenic testing.
Products: A. Dust, AP House Dust MixEnoxaparin
go.drugbank.com/drugs/DB01225ApprovedInvestigationalEnoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. … Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.
Products: ./0.6ML FER, ./0.8ML FERAnkle spasticity following a stroke or traumatic brain injury
go.drugbank.com/conditions/DBCOND0133858Drugs: Clostridium botulinumSynonyms: Ankle spasticity following a stroke or traumatic brain injury3-hydroxy-3-methylglutaryl-coenzyme A reductase
go.drugbank.com/bio_entities/BE0000574TargetEnzymeHumansHMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668, PubMed:36745799) … Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular
Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseFunction: coenzyme A bindingAcetyl-coenzyme A synthetase 2-like, mitochondrial
go.drugbank.com/bio_entities/BE0000746TargetHumansInvolved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity) … Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity).
Polypeptides: Acetyl-coenzyme A synthetase 2-like, mitochondrial2-amino-3-ketobutyrate coenzyme A ligase
go.drugbank.com/bio_entities/BE0002049TargetEscherichia coli (strain K12)Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
Polypeptides: 2-amino-3-ketobutyrate coenzyme A ligase2,5-diketo-D-gluconic acid reductase A
go.drugbank.com/bio_entities/BE0002618TargetCorynebacterium sp. (strain ATCC 31090)Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity
Polypeptides: 2,5-diketo-D-gluconic acid reductase ASynonyms: 2,5-DKG reductase AA-type voltage-gated potassium channel KCND2
go.drugbank.com/bio_entities/BE0003603TargetHumansIn vivo, membranes probably contain a mixture of heteromeric potassium channel complexes. … Functions downstream of the metabotropic glutamate receptor GRM5 and plays a role in neuronal excitability and in nociception mediated by activation of GRM5 (By similarity).
Polypeptides: A-type voltage-gated potassium channel KCND2Function: A-type (transient outward) potassium channel activityA-type voltage-gated potassium channel KCND3
go.drugbank.com/bio_entities/BE0003604TargetHumansIn neurons, may conduct the transient subthreshold somatodendritic A-type potassium current (ISA) (By similarity). … Pore-forming (alpha) subunit of voltage-gated A-type potassium channels that mediates transmembrane potassium transport in excitable membranes, in brain and heart (PubMed:10200233, PubMed:17187064, PubMed
Polypeptides: A-type voltage-gated potassium channel KCND3Function: A-type (transient outward) potassium channel activityA-type voltage-gated potassium channel KCND1
go.drugbank.com/bio_entities/BE0004726TargetHumansExhibits a low-threshold A-type current with a hyperpolarized steady-state inactivation midpoint and the recovery process was steeply voltage-dependent, with recovery being markedly faster at more negative … Mediates A-type current I(SA) in suprachiasmatic nucleus (SCN) neurons.
Polypeptides: A-type voltage-gated potassium channel KCND1Function: A-type (transient outward) potassium channel activity