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Displaying results 931 - 940 of 10000 in total
  1. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). … Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.

    Synonyms: Phospholipase C-deleted in lung carcinoma
  2. Target

    Gremlin-1

    go.drugbank.com/bio_entities/BE0011799
    TargetHumans

    Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). … Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback

    Synonyms: Increased in high glucose protein 2, Down-regulated in Mos-transformed cells protein
  3. Indication

    Glabellar Frown Lines (GL)

    go.drugbank.com/conditions/DBCOND0081153
    Drugs: Botulinum toxin type A
    Synonyms: Glabellar Lines, Glabellar Frown Lines
  4. Indication

    Splinter

    go.drugbank.com/conditions/DBCOND0015551
    Drugs: Ichthammol
    Synonyms: Splinter in skin (disorder)
  5. Target

    Cytoplasmic tyrosine-protein kinase BMX

    go.drugbank.com/bio_entities/BE0009416
    TargetHumans

    May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells … Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis.

    Synonyms: Bone marrow tyrosine kinase gene in chromosome X protein
  6. Indication

    Anorexia

    go.drugbank.com/conditions/DBCOND0004522
    Drugs: Dronabinol · Hemicellulase · Itopride · Megestrol acetate
    Synonyms: Decrease in appetite (finding)
  7. Indication

    Hyperglycemia

    go.drugbank.com/conditions/DBCOND0020377
    Drugs: Glycyrrhizic acid · Mifepristone
    Synonyms: High Level of Sugar (Glucose) in the Blood
  8. Indication

    Moderate Glabellar Frown Lines (GL)

    go.drugbank.com/conditions/DBCOND0146864
    Drugs: Botulinum toxin type A · DaxibotulinumtoxinA
    Synonyms: Moderate Glabellar Frown Lines (GL)
  9. Drug

    Hydroxyzine

    go.drugbank.com/drugs/DB00557
    ApprovedInvestigational

    [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect. … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus

    Products: Atarax Im Sol 50mg/ml
  10. Indication

    Pancreatic Metastatic Cancer

    go.drugbank.com/conditions/DBCOND0070216
    Drugs: Erlotinib · Leucovorin
    Synonyms: Secondary malignant deposit in pancreas