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Displaying results 931 - 940 of 10000 in total
  1. Target

    cAMP-dependent protein kinase (Protein kinase A)

    go.drugbank.com/bio_entities/BE0010127
    TargetHumans

    Phosphorylates a large number of substrates in the cytoplasm and the nucleus … Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR (PubMed:31112131)

  2. Drug

    Aloe vera leaf

    go.drugbank.com/drugs/DB13906
    ApprovedInvestigational

    It is a perennial succulent xerophyte with elongated leaves that contain a clear gel. … Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands.

    Mixtures: Re-action E, Alcortin ASynonyms: Barbatos aloe leaf
  3. Drug

    Cephalexin

    go.drugbank.com/drugs/DB00567
    ApprovedInvestigationalVet approved

    [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. … [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971.

    Synonyms: (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidInternational brands: L-Keflex
  4. Target

    V-type proton ATPase catalytic subunit A

    go.drugbank.com/bio_entities/BE0003569
    TargetHumans

    Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates … May play a role in neurite development and synaptic connectivity (PubMed:29668857)

    Polypeptides: V-type proton ATPase catalytic subunit ASynonyms: V-ATPase subunit A
  5. Target

    Nuclear receptor subfamily 4immunitygroup A member 1

    go.drugbank.com/bio_entities/BE0010494
    TargetHumans

    Plays a role in the vascular response to injury (By similarity)

    Polypeptides: Nuclear receptor subfamily 4immunitygroup A member 1
  6. Target

    Inositol polyphosphate-4-phosphatase type I A

    go.drugbank.com/bio_entities/BE0018619
    EnzymeHumans

    Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (PubMed:15716355, PubMed:20463662). Also catalyzes inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate (By similarity). ...

    Polypeptides: Inositol polyphosphate-4-phosphatase type I A
  7. Drug

    Hydrogen peroxide

    go.drugbank.com/drugs/DB11091
    ApprovedInvestigationalVet approved

    Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. … It is used in industrial and cosmetic applications as a bleaching agent.

    Mixtures: Defense AG Disinfectant, Defense AG DisinfectantCategories: Compounds used in a research, industrial, or household setting
  8. Target

    Vascular endothelial growth factor A, long form

    go.drugbank.com/bio_entities/BE0000163
    TargetHumans

    Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity)

    Polypeptides: Vascular endothelial growth factor A, long form
  9. Target

    3-hydroxy-3-methylglutaryl-coenzyme A reductase

    go.drugbank.com/bio_entities/BE0001856
    TargetPseudomonas mevalonii

    P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.

    Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
  10. Target

    ATP synthase F(0) complex subunit a

    go.drugbank.com/bio_entities/BE0009014
    TargetHumans

    These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).

    Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit a