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Displaying results 931 - 940 of 10000 in total
  1. Target

    Ephrin type-A receptor 7

    go.drugbank.com/bio_entities/BE0004140
    TargetHumans

    Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. … May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity.

    Polypeptides: Ephrin type-A receptor 7
  2. Target

    Acyl-coenzyme A thioesterase 13

    go.drugbank.com/bio_entities/BE0004376
    TargetHumans

    May play a role in controlling adaptive thermogenesis (By similarity) … Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545).

    Polypeptides: Acyl-coenzyme A thioesterase 13
  3. Target

    Ras-related protein Ral-A

    go.drugbank.com/bio_entities/BE0004562
    TargetHumans

    Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. … Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling (PubMed:20005108).

    Polypeptides: Ras-related protein Ral-A
  4. Target

    Serum amyloid A-1 protein

    go.drugbank.com/bio_entities/BE0004795
    TargetHumans

    Major acute phase protein

    Polypeptides: Serum amyloid A-1 protein
  5. Target

    Ephrin type-A receptor 3

    go.drugbank.com/bio_entities/BE0009437
    TargetHumans

    Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5 (By similarity). … Also activated by EFNA1, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development (PubMed:12794130). Involved in the retinotectal mapping of neurons.

    Polypeptides: Ephrin type-A receptor 3
  6. Target

    Ephrin type-A receptor 6

    go.drugbank.com/bio_entities/BE0009439
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

    Polypeptides: Ephrin type-A receptor 6
  7. Target

    GABA-A gated chloride channel

    go.drugbank.com/bio_entities/BE0009556
    TargetOnchocerca volvulus

  8. Target

    ATP-dependent RNA helicase A

    go.drugbank.com/bio_entities/BE0014303
    TargetHumans

    Plays a role as a transcriptional coactivator acting as a bridging factor between polymerase II holoenzyme and transcription factors or cofactors, such as BRCA1, CREBBP, RELA and SMN1 (PubMed:11038348, … Plays a role in mRNA translation (PubMed:28355180).

    Polypeptides: ATP-dependent RNA helicase ASynonyms: RNA helicase A
  9. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract. … Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization.

    Mixtures: Kank-A with Blistex Medicated Lip, Au Kah Chuen Skin LotionCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Hydrogen peroxide

    go.drugbank.com/drugs/DB11091
    ApprovedInvestigationalVet approved

    Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. … It is used in industrial and cosmetic applications as a bleaching agent.

    Mixtures: Defense AG Disinfectant, Defense AG DisinfectantCategories: Compounds used in a research, industrial, or household setting