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Displaying results 941 - 950 of 10000 in total
  1. Target

    Acetyl-coenzyme A synthetase, cytoplasmic

    go.drugbank.com/bio_entities/BE0000350
    TargetEnzymeHumans

    Can also utilize propionate with a much lower affinity (PubMed:38369012). Catalyzes the conversion of lactate into lactoyl-CoA (PubMed:39561764). … Acts as a chromatin-bound transcriptional coactivator that up-regulates histone acetylation and expression of neuronal genes (By similarity).

    Polypeptides: Acetyl-coenzyme A synthetase, cytoplasmic
  2. Target

    Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000377
    TargetHumans

    Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes (By similarity) … Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion

    Polypeptides: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialSynonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase
  3. Target

    Ephrin type-A receptor 2

    go.drugbank.com/bio_entities/BE0000841
    TargetHumans

    With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis … May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.

    Polypeptides: Ephrin type-A receptor 2
  4. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0001557
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase A
  5. Target

    Inositol-trisphosphate 3-kinase A

    go.drugbank.com/bio_entities/BE0001627
    TargetHumans

    Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis

    Polypeptides: Inositol-trisphosphate 3-kinase ASynonyms: IP3K A, IP3 3-kinase A
  6. Target

    Complement C1q subcomponent subunit A

    go.drugbank.com/bio_entities/BE0002094
    TargetHumans

    The C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM (PubMed:19706439, PubMed:24626930, PubMed:29449492). … Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens

    Polypeptides: Complement C1q subcomponent subunit A
  7. Target

    Amine oxidase [flavin-containing] A

    go.drugbank.com/bio_entities/BE0002198
    TargetEnzymeHumans

    Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amin...

    Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type A
  8. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0002739
    TargetClostridium stercorarium

    Endoxylanase that degrades arabinoxylan and glucuronoxylan to xylobiose and xylotriose (in vitro).

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: 1,4-beta-D-xylan xylanohydrolase A
  9. Target

    Endo-1,4-beta-xylanase A

    go.drugbank.com/bio_entities/BE0003244
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Endo-1,4-beta-xylanase ASynonyms: Xylanase A, 1,4-beta-D-xylan xylanohydrolase A
  10. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0008383
    TargetStaphylococcus aureus

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A