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Displaying results 951 - 960 of 8696 in total
  1. Pathway

    Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin

    smpdb.ca/view/SMP0000354
    Signaling

    The receptor is a G-protein coupled receptor, upon its binding it activates G proteins causing the activation of adenylyl cyclase and production of cAMP messenger molecules. cAMP activates PKA (protein … Prostacyclin binding to its receptor increases vasodilation and decreases platelet aggregation.

    Drugs: ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Prostacyclin receptor
  2. Pathway

    Trimebutine M3 Receptor Intestine Relaxation Action Pathway

    smpdb.ca/view/SMP0126338
    Drug action

    Possible side effects of using trimebutine may include dry mouth, heartburn, nausea, and drowsiness.

    Drugs: ATP · Nitric Oxide · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate +3 more
    Enzymes: Mu-type opioid receptor, Muscarinic acetylcholine receptor M3
  3. Indication

    Transient Ischemic Attack

    go.drugbank.com/conditions/DBCOND0029275
    Drugs: Acenocoumarol · Acetylsalicylic acid · Atorvastatin · Dipyridamole · Glycine · Nicergoline +2 more
  4. Drug

    Imidapril

    go.drugbank.com/drugs/DB11783
    Investigational

    Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.

    Products: PRILIUM 150MG POWDER FOR ORAL SOLUTION
  5. Drug

    Venlafaxine

    go.drugbank.com/drugs/DB00285
    ApprovedInvestigational

    [A252065] Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years. … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI).

    Categories: Antidepressive Agents Indicated for Depression, P-glycoprotein inhibitorsProducts: Mar-venlafaxine XR
  6. Drug

    Flutemetamol

    go.drugbank.com/drugs/DB15058
    Investigational

    Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).

    Products: VIZAMYL SOLUTION FOR INJECTION 150 MBq/mL
  7. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments.

    Synonyms: p-chloro-m-xylenol, p-chloro-3,5-xylenolProducts: Ban-Aid, Ps-1000
  8. Drug

    WU-CART-007

    go.drugbank.com/drugs/DB18617
    Investigational

    WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.

    Synonyms: an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7
  9. Drug

    Cloprostenol

    go.drugbank.com/drugs/DB11507
    ExperimentalVet approved

    Categories: Hormonal Contraceptives for Systemic UseProducts: GESTAVET PROST (d-cloprostenol 75 mcg/ml solution for injection)
  10. Drug

    Arginine

    go.drugbank.com/drugs/DB00125
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is physiologically active in the L-form.

    Mixtures: Aminosyn-PF, Aminosyn-PFCategories: Detoxifying Agents for Antineoplastic Treatment