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Nuclear receptor subfamily 4 group A member 3
go.drugbank.com/bio_entities/BE0008998TargetHumansTranscriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. … Binds to NBRE motif in CCND1 promoter, resulting in the activation of the promoter and CCND1 transcription (By similarity).
Synonyms: Translocated in extraskeletal chondrosarcomaSerine/threonine-protein kinase Nek4
go.drugbank.com/bio_entities/BE0009498TargetHumansRequired for normal cell cycle arrest in response to double-stranded DNA damage
Synonyms: Never in mitosis A-related kinase 4Risperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigationalRisperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain. … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder.
Products: RISPERDAL CONSTA 25 mg IM ENJEKSİYONLUK UZATILMIŞ SALIMLI SÜSPANSİYON, 1 ADET, RISPERDAL CONSTA 50 mg IM ENJEKSİYONLUK UZATILMIŞ SALIMLI SÜSPANSİYON, 1 ADETDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalin the epithelium[A32373]. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism
Mixtures: Daily all in one ample, Daily all in one ampleSynonyms: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamideNasal Polyps
go.drugbank.com/conditions/DBCOND0004147Drugs: BudesonideSynonyms: Polyp in anterior naresChronic Phase Chronic Myeloid Leukemia
go.drugbank.com/conditions/DBCOND0057382Synonyms: CML in Chronic Phase, Chronic Myeloid Leukemia in Chronic PhaseDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]
Products: Vibramycin InjStromal cell-derived factor 1
go.drugbank.com/bio_entities/BE0001150TargetHumansInduces down-regulation and internalization of ACKR3 expressed in various cells. … Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 in a CXCR4-independent manner (PubMed:29301984).
Synonyms: Intercrine reduced in hepatomasWater
go.drugbank.com/drugs/DB09145ApprovedInvestigationalWater is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with its solid state, ice; and gaseous state, steam (water vapor). … Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms.
Mixtures: IC-Green, IC-GreenProducts: TACEX-IM, N/ANuclear factor NF-kappa-B p100 subunit
go.drugbank.com/bio_entities/BE0002387TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2