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Ergoloid mesylate Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126658Drug actionErgoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortThiethylperazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126476Drug actionThiethylperazine' s antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors.
Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Thiethylperazine · Dopamine · Levodopa +2 moreEnzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortAnileridine
go.drugbank.com/drugs/DB00913ApprovedIllicitWithdrawnAnileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain.
Synonyms: 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester, ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylateCategories: Heterocyclic Compounds, 1-RingMegestrol acetate Action Pathway
smpdb.ca/view/SMP0126528Drug actionMegestrol acetate is a synthetic progestational hormone initially developed as a contraceptive. Nowadays, it is used as a drug to treat anorexia and cachexia (or unexplained weight loss) and as an antineoplastic agent to treat inoperable...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Norelgestromin Action Pathway
smpdb.ca/view/SMP0126539Drug actionNorelgestromin is a synthetic progestational hormone indicated in women to prevent pregnancy. This drug is also used in menopausal hormonal therapy. This drug is administered as a contraceptive pill or as a transdermal patch. This drug i...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Ziprasidone Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126472Drug actionZiprasidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and acute agitation in schizophrenic patients. It also indicated improvement on the manic syndrome subscale that measures symptoms of mania such as mood...
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's disease
Mixtures: EMAXIN BASLANGIC SETI, 7+7+7+7 ADET, EMAXIN BASLANGIC SETI, 7+7+7+7 ADETCategories: N-methyl-D-aspartate Receptor Antagonist, Cytochrome P-450 CYP2A6 InhibitorsEtonogestrel Action Pathway
smpdb.ca/view/SMP0126525Drug actionEtonogestrel is a synthetic metabolite of progestin desosgestrel. This drug is a long-acting progestin contraceptive used mostly in intradermal implants that are releasing 40 mcg/day of the drug for 3 years. Etonogestrel binds strongly t...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Progesterone Action Pathway
smpdb.ca/view/SMP0126529Drug actionProgesterone is a hormone naturally occurring in females. This molecule is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. It is used as an oral drug as a contraceptive to preven...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Norethisterone Action Pathway
smpdb.ca/view/SMP0126536Drug actionNorethisterone, also known as norethindrone, is a synthetic progestational hormone used for contraception, prevention of endometrial hyperplasia (hormone replacement therapy), and in the treatment of other hormone-related illnesses. This...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12