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Displaying results 971 - 980 of 10000 in total
  1. Drug

    Butenafine

    go.drugbank.com/drugs/DB01091
    Approved

    Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols.

    Synonyms: (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamineProducts: Tinactin Once-A-day Cream, BUTEFIN %1 KREM, 15 G
  2. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.

    Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
  3. Drug

    Ertapenem

    go.drugbank.com/drugs/DB00303
    ApprovedInvestigational

    Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics.[L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid, (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  4. Drug

    Benzylpenicillin

    go.drugbank.com/drugs/DB01053
    ApprovedInvestigationalVet approved

    Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci … It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption.

    Synonyms: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-phenylacetamido)penicillanic acidMixtures: Bicillin A-P Injection Pws, Bicillin A-P Injection Pws
  5. Indication

    Headaches NEC

    go.drugbank.com/conditions/DBCOND0026466
    Drugs: Acetaminophen · Acetylsalicylic acid · Bromopride · Brompheniramine · Caffeine · Carbaspirin calcium +15 more
    Synonyms: C/O - a headache, Complaining of a headache
  6. Drug

    Turoctocog alfa

    go.drugbank.com/drugs/DB09109
    Approved

    Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally … During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification

    Products: NOVOEIGHT® 1500 UI POLVO ESTERIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, NOVOEIGHT®500UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE
  7. Drug

    Carboxymethylcellulose

    go.drugbank.com/drugs/DB11059
    ApprovedInvestigational

    It is added in food products as a viscosity modifier or thickener and emulsifier. … Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.

    Mixtures: OPTIVE ®, OPTIVE ®Categories: Compounds used in a research, industrial, or household setting
  8. Indication

    Tremor

    go.drugbank.com/conditions/DBCOND0003658
    Drugs: Bornaprine · Diazepam
    Synonyms: Has a tremor, (Has a tremor) or (tremor symptom) or (shaking)
  9. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists.

    Mixtures: Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2%, Dapsone 6% / Niacinamide 2% / Spironolactone 5%Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 Inhibitors
  10. Target

    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

    go.drugbank.com/bio_entities/BE0004581
    TargetHumans

    Essential component of the WICH-5 ISWI chromatin-remodeling complex (also called the WICH complex), a chromatin-remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular … Within the B-WICH complex has a role in RNA polymerase III transcription (PubMed:16603771).

    Polypeptides: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5