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Dihydrocodeine
go.drugbank.com/drugs/DB01551ApprovedIllicitDihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. … It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis
Mixtures: Duohist DH, EndaCof DHCategories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeIsoleucine
go.drugbank.com/drugs/DB00167ApprovedInvestigationalNutraceuticalAn essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Mixtures: SOLUCION DP-AMINE, TRAVASOL PLUS 15% LIBRE DE BISULFITOOxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. … [A229108,A229113] It is estimated that labor induction with oxytocin is used in almost 10% of deliveries globally.
Categories: Increased Uterine Smooth Muscle Contraction or ToneProducts: Oxyla 10 IU/mL Injection, SYNTOCINON INJECTION 10 iu/mlPeginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnChemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. … Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine. FDA approved March 27, 2012.
Categories: Compounds used in a research, industrial, or household settingHuman thrombin
go.drugbank.com/drugs/DB11571ApprovedInvestigationalHuman thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. … Furthermore, human thrombin is manufactured by chromatographic purification of prothrombin from cryo-poor plasma followed by activation with calcium chloride [FDA Label].
Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml, EVICEL® SELLANTE DE FIBRINA HUMANASodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedWhen dissolved in water or neutralized with acid it releases substantial amounts of heat, which may prove sufficient to ignite combustible materials. Sodium hydroxide is highly corrosive [L1965]. … Sodium hydroxide is also known as _lye_ or _soda_ , or _caustic soda_ [L1971]. At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air.
Mixtures: Vamin N, NUTRIFLEX PERI IN 2000ML TWIN-FLEXCategories: Compounds used in a research, industrial, or household settingInclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigational[L28178] Inclisiran was later approved by the FDA on December 22, 2021, for the treatment of heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease in adults … [A225953,A225958] On December 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and only approved siRNA for the treatment of adults with primary hypercholesterolemia
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingProducts: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, Sybrava 284mg/1.5ml Solution for Injection in Pre-filled SyringeButamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnThe FDA removed all parenteral butamben products from the market, possibly due to the poor solubility of this drug.[A254247,L43942] … Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate.
Mixtures: One Touch Advanced Topical Anesthetic Cherry, One Touch Advanced Topical Anesthetic Gel Cool MintEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedLactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120] … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.
Mixtures: Ti-U-lac Lotion, SOLUCION DE RINGER CON LACTATOSynonyms: DL-Milchsäure, DL-Lactic Acid