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Lactoylglutathione lyase
go.drugbank.com/bio_entities/BE0000962TargetEnzymeHumansCatalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294).
Synonyms: S-D-lactoylglutathione methylglyoxal lyaseHydroxymycolate synthase MmaA4
go.drugbank.com/bio_entities/BE0003863TargetMycobacterium tuberculosisProbably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation
Synonyms: S-adenosylmethionine-dependent methyltransferasePrimary Immune Deficiency Disorders (PIDD)
go.drugbank.com/conditions/DBCOND0038807Synonyms: Primary Immunodeficiency Disease(s)Cyanocobalamin reductase / alkylcobalamin dealkylase
go.drugbank.com/bio_entities/BE0002175TargetHumansCobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...
Synonyms: Alkylcobalamin:glutathione S-alkyltransferaseEukaryotic peptide chain release factor GTP-binding subunit ERF3A
go.drugbank.com/bio_entities/BE0004448TargetHumansGTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GS...
Synonyms: G1 to S phase transition protein 1 homologGabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalGabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.
Mixtures: Innoprax-5, GAVINDO NSynonyms: 1-(Aminomethyl)cyclohexaneacetic acidAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedThe primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near the skin surface [A27159]. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.
Mixtures: KURSEPT %19 + %1 KREM (30 G), PERS-MANT %19 + %2 JEL (30 G)Products: Charm-Tex Deodorant, Lemon Ginger Tea DeodorantIodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalIodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. … As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, while the other 90% (beta radiation) causes tissue damage without contributing to any ability to see
Salts: Sodium iodide I-131Synonyms: 131 I, 131-IPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]
Mixtures: Ryna -12 S, Stona-SCategories: Adrenergic alpha-1 Receptor Agonists, Monoamine Oxidase A SubstratesPeptidoglycan editing factor PgeF
go.drugbank.com/bio_entities/BE0002757TargetEscherichia coli (strain K12)Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (PubMed:31978345). Also has adenosine deaminase activity (PubMed:31978345).
Synonyms: S-methyl-5'-thioadenosine phosphorylase, S-methyl-5'-thioadenosine phosphorylase YfiH