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Collagen alpha-1(I) chain
go.drugbank.com/bio_entities/BE0000025TargetHumansType I collagen is a member of group I collagen (fibrillar forming collagen)
Polypeptides: Collagen alpha-1(I) chainSynonyms: Alpha-1 type I collagenCollagen alpha-2(I) chain
go.drugbank.com/bio_entities/BE0002141TargetHumansType I collagen is a member of group I collagen (fibrillar forming collagen)
Polypeptides: Collagen alpha-2(I) chainSynonyms: Alpha-2 type I collagenCollagen alpha-1(III) chain
go.drugbank.com/bio_entities/BE0002130TargetHumansCollagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. … Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12
Polypeptides: Collagen alpha-1(III) chainCollagen alpha-4(IV) chain
go.drugbank.com/bio_entities/BE0003498TargetHumansType IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen
Polypeptides: Collagen alpha-4(IV) chainCollagen alpha-1(II) chain
go.drugbank.com/bio_entities/BE0002140TargetHumansType II collagen is specific for cartilaginous tissues. … It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces
Polypeptides: Collagen alpha-1(II) chainSynonyms: Alpha-1 type II collagenCollagen alpha-1(VII) chain
go.drugbank.com/bio_entities/BE0014000TargetHumans(ECM) proteins such as type IV collagen … Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix
Polypeptides: Collagen alpha-1(VII) chainSynonyms: LC collagen, Long-chain collagenDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
go.drugbank.com/bio_entities/BE0001300TargetHumansMay act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K
Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositideSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
go.drugbank.com/bio_entities/BE0000423TargetTransporterHumansTransports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine (PubMed:18599538). … Can also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-) (PubMed:17855766)
Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)B- and T-lymphocyte attenuator
go.drugbank.com/bio_entities/BE0010629TargetHumansInhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). … In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state.
Polypeptides: B- and T-lymphocyte attenuatorSynonyms: B- and T-lymphocyte-associated proteinSplicing factor, proline- and glutamine-rich
go.drugbank.com/bio_entities/BE0008965TargetHumansThe SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. … DNA- and RNA binding protein, involved in several nuclear processes.
Polypeptides: Splicing factor, proline- and glutamine-rich