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Evolocumab

go.drugbank.com/drugs/DB09303
ApprovedInvestigational

Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering. It is approved for both homozygous and heterozygous familial cholesterolemia a...

  1. Pathway

    Evolocumab Action Pathway

    smpdb.ca/view/SMP0125309
    Drug action

    Evolocumab is indicated in adult patients with established cardiovascular disease to reduce the risk of myocardial infarction, stroke, and coronary revascularization. … Evolocumab is a PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor antibody used as an adjunct to LDL cholesterol reducing therapies, aiding in the prevention of cardiovascular events and

    Drugs: Calcium · Cholesterol · Evolocumab
  2. Indication

    Unstable Angina Pectoris

    go.drugbank.com/conditions/DBCOND0032056
    Drugs: Alirocumab · Evolocumab · Fondaparinux · Heparin · Lovastatin · Molsidomine +2 more
  3. Drug

    Enlicitide

    go.drugbank.com/drugs/DB22580
    ApprovedInvestigational

    [L63795] Unlike the monoclonal antibody PCSK9 inhibitors ([evolocumab], [alirocumab]), enlicitide is administered orally as a once-daily tablet.

  4. Indication

    Cardiovascular Mortality

    go.drugbank.com/conditions/DBCOND0040959
    Drugs: Acetylsalicylic acid · Canagliflozin · Colchicine · Dapagliflozin · Empagliflozin · Evolocumab +12 more
  5. Indication

    Myocardial Infarction

    go.drugbank.com/conditions/DBCOND0027900
    Drugs: Acetylsalicylic acid · Alirocumab · Atenolol · Atorvastatin · Bempedoic acid · Colchicine +13 more
  6. Indication

    Stroke

    go.drugbank.com/conditions/DBCOND0020609
    Drugs: Acetylsalicylic acid · Alirocumab · Apixaban · Atorvastatin · Cerebrolysin · Choline alfoscerate +14 more