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Displaying results 1 - 10 of 42 in total
  1. Drug

    Pheniramine

    go.drugbank.com/drugs/DB01620
    Approved

    Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … Pheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as [cetirizine] and [loratadine].

    Synonyms: Pheniramine, PheniraminumSalts: Pheniramine maleate
  2. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. … Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609].

    Synonyms: NaphazolineSalts: Naphazoline hydrochloride, Naphazoline nitrate
  3. Pathway

    Pheniramine H1-Antihistamine Action

    smpdb.ca/view/SMP0056662
    Drug action

    Pheniramine is a first-generation alkylamine H1-antihistamine. … conjunctivitis, and urticaria.

    Drugs: Calcium · Pheniramine
  4. Pathway

    Pheniramine Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174551
    Metabolic

    Metabolites of Pheniramine are predicted with biotransformer.

    Drugs: Pheniramine · Mesoheme
  5. Pathway

    Pheniramine H1 Antihistamine Neurological Sleep Action Pathway

    smpdb.ca/view/SMP0145419
    Drug action

    Pheniramine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. … Pheniramine inhibits the H1 histamine receptor, preventing the depolarization of the post-synaptic neuron.

    Drugs: Pyridoxal phosphate · Histidine · Calcium · Pheniramine
  6. Pathway

    Pheniramine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0175091
    Drug action

    Pheniramine is an antihistamine used to treat allergic rhinitis and pruritus. … conjunctivitis, and urticaria.

    Drugs: Calcium · Pheniramine
  7. Pathway

    Pheniramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0174907
    Drug action

    Pheniramine is an antihistamine used to treat allergic rhinitis and pruritus. … Allergies causes blood vessel dilation which causes swelling (edema) and fluid leakage. Pheniramine also inhibits the H1 histamine receptor on bronchiole smooth muscle myocytes.

    Drugs: Calcium · Magnesium cation · Pheniramine
  8. Pathway

    Pheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway

    smpdb.ca/view/SMP0174999
    Drug action

    Pheniramine is an antihistamine used to treat allergic rhinitis and pruritus. … Allergies causes blood vessel dilation which causes swelling (edema) and fluid leakage. Pheniramine inhibits the H1 histamine receptor on blood vessel endothelial cells.

    Drugs: Arginine · Citrulline · Sapropterin · Nitric Oxide · Calcium · Magnesium cation +4 more
  9. Indication

    Angioedema

    go.drugbank.com/conditions/DBCOND0013604
    Drugs: Carbinoxamine · Clemastine · Dexchlorpheniramine maleate · Diphenhydramine · Pheniramine
    Synonyms: Angioedema and urticaria
  10. Indication

    Dacryostenosis

    go.drugbank.com/conditions/DBCOND0125516
    Drugs: Naphazoline