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Displaying results 1 - 10 of 14 in total
  1. Target

    Riboflavin kinase

    go.drugbank.com/bio_entities/BE0000370
    TargetHumans

    Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD.

    Polypeptides: Riboflavin kinaseFunction: riboflavin kinase activity
  2. Target

    Riboflavin synthase

    go.drugbank.com/bio_entities/BE0003327
    TargetEscherichia coli (strain K12)

    Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

    Polypeptides: Riboflavin synthaseFunction: riboflavin synthase activity
  3. Target

    Riboflavin biosynthesis protein

    go.drugbank.com/bio_entities/BE0002551
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Riboflavin biosynthesis protein
  4. Target

    Solute carrier family 52, riboflavin transporter, member 3

    go.drugbank.com/bio_entities/BE0019983
    TransporterHumans

    Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145) … Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino

    Polypeptides: Solute carrier family 52, riboflavin transporter, member 3Synonyms: Riboflavin transporter 2
  5. Target

    Solute carrier family 52, riboflavin transporter, member 2

    go.drugbank.com/bio_entities/BE0004841
    TargetTransporterHumans

    Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145). May also act as a receptor for 4-hydroxybutyrate (Probable) … Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino

    Polypeptides: Solute carrier family 52, riboflavin transporter, member 2Synonyms: Riboflavin transporter 3
  6. Target

    6,7-dimethyl-8-ribityllumazine synthase

    go.drugbank.com/bio_entities/BE0001767
    TargetBacillus subtilis (strain 168)

    This is the penultimate step in the biosynthesis of riboflavin.

    Synonyms: Heavy riboflavin synthase beta subunit
  7. Target

    Major NAD(P)H-flavin oxidoreductase

    go.drugbank.com/bio_entities/BE0001226
    TargetVibrio fischeri

    As electron acceptor, FMN is the most effective, FAD is considerably effective, and riboflavin is the least effective.

  8. Target

    Major histocompatibility complex class I-related protein 1

    go.drugbank.com/bio_entities/BE0003573
    TargetHumans

    In complex with B2M preferentially presents riboflavin-derived metabolites to semi-invariant TRAV1.2 TCRs on MAIT cells, guiding immune surveillance of the microbial metabolome at mucosal epithelial barriers … Signature pyrimidine-based microbial antigens are generated via non-enzymatic condensation of metabolite intermediates of the riboflavin pathway with by-products arising from other metabolic pathways such

  9. Target

    Bifunctional FAD diphosphatase/FAD synthase

    go.drugbank.com/bio_entities/BE0017310
    EnzymeHumans

    FAD synthase cannot convert 8-demethyl-8-amino-riboflavin mononucleotide (AFMN) to 8-demethyl-8-amino-riboflavin adenine dinucleotide (AFAD); AFMN is produced by riboflavin kinase when acting on the antibiotic … 8-demethyl-8-amino-riboflavin (AF) (PubMed:21924249)

  10. Target

    Broad substrate specificity ATP-binding cassette transporter ABCG2

    go.drugbank.com/bio_entities/BE0001067
    TargetTransporterCarrierHumans

    Mediates the secretion of the vitamins riboflavin and biotin into milk (By similarity). … Involved in the excretion of the riboflavin-derived compound lumichrome into the intestinal lumen and in its secretion into milk (PubMed:39337371).