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Displaying all 8 results
  1. Target

    Potassium channel subfamily K member 18

    go.drugbank.com/bio_entities/BE0016097
    TargetHumans

    K(+) channel that conducts outward and inward rectifying currents at depolarized and hyperpolarized membrane potentials, respectively. The outward rectifying currents are voltage-dependent, coupled to K(+) electrochemical gradient across...

    Synonyms: TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel
  2. Target

    Potassium channel subfamily K member 6

    go.drugbank.com/bio_entities/BE0000680
    TargetHumans

    K(+) channel that conducts outward rectifying currents at the membranes of the endolysosomal system (PubMed:10887187, PubMed:28381826, PubMed:40343992, PubMed:41617707). Active in lysosomes where it regulates lysosome numbers and size (P...

    Synonyms: TWIK-originated similarity sequence, Inward rectifying potassium channel protein TWIK-2
  3. Target

    Coagulation factor X

    go.drugbank.com/bio_entities/BE0000216
    TargetEnzymeHumans

    Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting (PubMed:22409427, PubMed:39880037). Factor Xa activates pro-inflammatory s...

    Synonyms: Stuart-Prower factor
  4. Target

    Potassium channel subfamily K member 1

    go.drugbank.com/bio_entities/BE0000154
    TargetHumans

    Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues (PubMed:15820677, PubMed:21653227). Forms dime...

    Synonyms: Inward rectifying potassium channel protein TWIK-1
  5. Target

    Potassium channel subfamily K member 3

    go.drugbank.com/bio_entities/BE0003582
    TargetHumans

    K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens t...

    Synonyms: TWIK-related acid-sensitive K(+) channel 1
  6. Target

    Potassium channel subfamily K member 9

    go.drugbank.com/bio_entities/BE0003583
    TargetHumans

    K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens t...

    Synonyms: TWIK-related acid-sensitive K(+) channel 3
  7. Target

    Nucleoside diphosphate kinase A

    go.drugbank.com/bio_entities/BE0003106
    TargetEnzymeHumans

    Catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving a phosphohistidine intermediate, therefore contributing to the nucleoside trip...

    Synonyms: Tumor metastatic process-associated protein
  8. Target

    Nucleoside diphosphokinase

    go.drugbank.com/bio_entities/BE0009626
    EnzymeHumans

    Catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving a phosphohistidine intermediate, therefore contributing to the nucleoside trip...

    Synonyms: Tumor metastatic process-associated protein