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Displaying results 1 - 10 of 93 in total
  1. Target

    Galectin-10

    go.drugbank.com/bio_entities/BE0001886
    TargetHumans

    Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg)

    Polypeptides: Galectin-10Synonyms: Gal-10
  2. Target

    Frizzled-10

    go.drugbank.com/bio_entities/BE0020969
    TargetHumans

    Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclea...

    Polypeptides: Frizzled-10Synonyms: Fz-10
  3. Target

    Interleukin-10

    go.drugbank.com/bio_entities/BE0002484
    TargetHumans

    Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetram...

    Polypeptides: Interleukin-10Synonyms: IL-10
  4. Target

    Aquaporin-10

    go.drugbank.com/bio_entities/BE0018706
    TransporterHumans

    Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:11573934, PubMed:12084581, PubMed:217338...

    Polypeptides: Aquaporin-10Synonyms: AQP-10, Aquaglyceroporin-10
  5. Target

    Monocarboxylate transporter 10

    go.drugbank.com/bio_entities/BE0003654
    TransporterHumans

    Sodium- and proton-independent thyroid hormones and aromatic acids transporter (PubMed:11827462, PubMed:18337592, PubMed:28754537). Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) wit...

    Polypeptides: Monocarboxylate transporter 10Synonyms: MCT 10, Solute carrier family 16 member 10
  6. Target

    Beta-lactamase OXA-10

    go.drugbank.com/bio_entities/BE0001274
    TargetEnzymePseudomonas aeruginosa

    Hydrolyzes both carbenicillin and oxacillin.

    Polypeptides: Beta-lactamase OXA-10
  7. Target

    Cytosolic 10-formyltetrahydrofolate dehydrogenase

    go.drugbank.com/bio_entities/BE0000933
    TargetHumans

    Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436).

    Polypeptides: Cytosolic 10-formyltetrahydrofolate dehydrogenaseSynonyms: 10-FTHFDH
  8. Target

    Bone morphogenetic protein 10

    go.drugbank.com/bio_entities/BE0010910
    TargetHumans

    Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors s...

    Polypeptides: Bone morphogenetic protein 10Synonyms: BMP-10
  9. Target

    Aclacinomycin 10-hydroxylase RdmB

    go.drugbank.com/bio_entities/BE0002526
    TargetStreptomyces purpurascens

    In vivo and in vitro, RdmB catalyzes the removal of the carboxylic group from the C-10 position of 15-demethoxyaclacinomycin T coupled to hydroxylation at the same C-10 position. … It could also catalyze the removal of the carboxylic group at the C-10 position of 15-demethoxy-epsilon-rhodomycin coupled to hydroxylation at the same C-10 position to yield rhodomycin B.

    Polypeptides: Aclacinomycin 10-hydroxylase RdmBSynonyms: 15-demethoxy-epsilon-rhodomycin 10-hydroxylase
  10. Target

    Immunoglobulin superfamily member 10

    go.drugbank.com/bio_entities/BE0004612
    TargetHumans

    Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons) (By similarity). May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity)

    Polypeptides: Immunoglobulin superfamily member 10