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Displaying results 1 - 10 of 63 in total
  1. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutase
  2. Target

    Receptor for retinol uptake STRA6

    go.drugbank.com/bio_entities/BE0009879
    TransporterHumans

    Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid (PubMed:18316031). … ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed:21368206, PubMed:22665496).

    Polypeptides: Receptor for retinol uptake STRA6
  3. Target

    cDNA FLJ60754, moderately similar to Survival motor neuron protein

    go.drugbank.com/bio_entities/BE0009143
    TargetHumans

    Polypeptides: cDNA FLJ60754, moderately similar to Survival motor neuron proteinSynonyms: cDNA FLJ60754, moderately similar to Survival motor neuron protein
  4. Target

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

    go.drugbank.com/bio_entities/BE0001300
    TargetHumans

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K

    Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
  5. Target

    Protein RIC-3

    go.drugbank.com/bio_entities/BE0009005
    TargetHumans

    Molecular chaperone which facilitates proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) and alpha-8 (CHRNA8) nicotinic acetylcholine receptors (PubMed:12821669, PubMed:15504725, PubMed:16120769, PubMed:18691158, PubMed:...

    Synonyms: Resistant to inhibitor of cholinesterase 3
  6. Target

    Advanced glycation end product-specific receptor

    go.drugbank.com/bio_entities/BE0010032
    TransporterTargetHumans

    Protects cells from DNA replication stress by localizing to damaged replication forks where it stabilizes the MCM2-7 complex and promotes faithful progression of the replication fork (PubMed:36807739). … Promotes NPP-mediated phagocytosis of Saccharomyces cerevisiae spores by binding to RNA attached to the spore wall (PubMed:35974093).

    Synonyms: Receptor for advanced glycation end products, Receptor for advanced glycosylation end products
  7. Target

    Chemotaxis protein CheA

    go.drugbank.com/bio_entities/BE0001431
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).

    Polypeptides: Chemotaxis protein CheA
  8. Target

    Calcium-dependent secretion activator 2

    go.drugbank.com/bio_entities/BE0008710
    TargetHumans

    Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development.

    Synonyms: Calcium-dependent activator protein for secretion 2
  9. Target

    Bile salt-activated lipase

    go.drugbank.com/bio_entities/BE0004523
    TargetEnzymeHumans

    Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs) (PubMed:10220579, PubMed:27509211, Pu...

    Polypeptides: Bile salt-activated lipaseSynonyms: Bile salt-stimulated lipase
  10. Target

    Bile salt hydrolase/transferase

    go.drugbank.com/bio_entities/BE0001392
    TargetClostridium perfringens (strain 13 / Type A)

    Shows a slight preference for taurine-conjugated bile acids as substrates (PubMed:7618863). … Also acts as an amine N-acyltransferase that conjugates a wide variety of amino acids to conjugated and non-conjugated bile acids, thus producing bacterial bile acid amidates (BBAAs) - also named microbially

    Polypeptides: Bile salt hydrolase/transferaseSynonyms: Bile salt hydrolase