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Displaying results 1 - 10 of 12 in total
  1. Target

    Pancreatic adenocarcinoma up-regulated factor

    go.drugbank.com/bio_entities/BE0018243
    TargetHumans

    Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth us...

    Polypeptides: Pancreatic adenocarcinoma up-regulated factor
  2. Target

    Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)

    go.drugbank.com/bio_entities/BE0003350
    TargetEscherichia coli (strain K12)

    Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). … UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.

    Synonyms: uppS, UPP synthase
  3. Target

    Uroporphyrinogen decarboxylase

    go.drugbank.com/bio_entities/BE0001629
    TargetHumans

    Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:11069625, PubMed:11719352, PubMed:1463398...

    Synonyms: UPD
  4. Target

    Urokinase-type plasminogen activator

    go.drugbank.com/bio_entities/BE0000895
    TargetEnzymeHumans

    Serine protease that cleaves the inactive precursor plasminogen at a specific Arg-Val peptide bond, converting it into active plasmin (PubMed:1969415, PubMed:2521625, PubMed:4270330). Secreted as an inactive zymogen, it is recruited and ...

    Synonyms: uPA
  5. Target

    Uteroglobin

    go.drugbank.com/bio_entities/BE0004289
    TargetHumans

    Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2

    Synonyms: UP1, UP-1
  6. Target

    Uridine phosphorylase 1

    go.drugbank.com/bio_entities/BE0002456
    EnzymeTargetHumans

    Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (PubMed:7488099). Shows br...

    Synonyms: UP
  7. Target

    Non-secretory ribonuclease

    go.drugbank.com/bio_entities/BE0001306
    TargetHumans

    This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities

    Synonyms: RNase UpI-2
  8. Target

    Ribonuclease pancreatic

    go.drugbank.com/bio_entities/BE0003317
    TargetHumans

    Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA

    Synonyms: RNase UpI-1
  9. Target

    Heterogeneous nuclear ribonucleoprotein K

    go.drugbank.com/bio_entities/BE0009026
    TargetHumans

    One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-...

    Synonyms: Transformation up-regulated nuclear protein
  10. Target

    Thioredoxin-interacting protein

    go.drugbank.com/bio_entities/BE0019558
    TargetHumans

    May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability (PubMed:17603038). Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated...

    Synonyms: Vitamin D3 up-regulated protein 1