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Serine repeat antigen 5
go.drugbank.com/bio_entities/BE0009196TargetPlasmodium falciparumPolypeptides: Serine repeat antigen 5Baculoviral IAP repeat-containing protein 3
go.drugbank.com/bio_entities/BE0010674TargetHumansActs as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition
Polypeptides: Baculoviral IAP repeat-containing protein 3Baculoviral IAP repeat-containing protein 2
go.drugbank.com/bio_entities/BE0010675TargetHumansActs as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition
Polypeptides: Baculoviral IAP repeat-containing protein 2Baculoviral IAP repeat-containing protein 5
go.drugbank.com/bio_entities/BE0003408TargetHumansInvolved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis (PubMed:20929775).
Polypeptides: Baculoviral IAP repeat-containing protein 5Baculoviral IAP repeat-containing protein 7
go.drugbank.com/bio_entities/BE0010707TargetHumansApoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control (PubMed:11024045, PubMed:11084335, PubMed:11162435, PubMed:16729033, PubM...
Polypeptides: Baculoviral IAP repeat-containing protein 7Baculoviral IAP repeat-containing protein 1
go.drugbank.com/bio_entities/BE0010810TargetHumansAnti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...
Polypeptides: Baculoviral IAP repeat-containing protein 1Leucine-rich repeat-containing G protein-coupled receptor 5
go.drugbank.com/bio_entities/BE0010835TargetHumansReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with ph...
Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Leucine-rich repeat serine/threonine-protein kinase 2
go.drugbank.com/bio_entities/BE0009457TargetHumansIn addition, has GTPase activity via its Roc domain which regulates LRRK2 kinase activity (PubMed:18230735, PubMed:26824392, PubMed:28720718, PubMed:29125462, PubMed:29212815).
Polypeptides: Leucine-rich repeat serine/threonine-protein kinase 2F-box-like/WD repeat-containing protein TBL1X
go.drugbank.com/bio_entities/BE0012106TargetHumansF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units (PubMed:14980219). Plays an essential role in transcription activation mediated by nuclear receptors...
Polypeptides: F-box-like/WD repeat-containing protein TBL1XAnkyrin repeat and protein kinase domain-containing protein 1
go.drugbank.com/bio_entities/BE0009411TargetHumansPolypeptides: Ankyrin repeat and protein kinase domain-containing protein 1