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Displaying results 1 - 10 of 31 in total
  1. Target

    Bifunctional PGK/TIM

    go.drugbank.com/bio_entities/BE0001611
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Bifunctional PGK/TIMSynonyms: TIM
  2. Target

    L-allo-threonine aldolase

    go.drugbank.com/bio_entities/BE0002839
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: L-allo-threonine aldolaseFunction: L-allo-threonine aldolase activity
  3. Target

    Immunoglobulin heavy constant gamma 2

    go.drugbank.com/bio_entities/BE0003805
    TargetHumans

    Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...

    Synonyms: Ig gamma-2 chain C region TIL
  4. Target

    All-trans-retinol 13,14-reductase

    go.drugbank.com/bio_entities/BE0002320
    TargetHumans

    Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers.

    Polypeptides: All-trans-retinol 13,14-reductaseSynonyms: All-trans-13,14-dihydroretinol saturase
  5. Target

    Tyrosine-protein kinase receptor Tie-1

    go.drugbank.com/bio_entities/BE0009396
    TargetHumans

    Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis

    Polypeptides: Tyrosine-protein kinase receptor Tie-1Synonyms: TIE
  6. Target

    All-trans-retinol dehydrogenase [NAD(+)] ADH7

    go.drugbank.com/bio_entities/BE0000522
    TargetEnzymeHumans

    Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal (PubMed:15369820, PubMed:16787387). … Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid (PubMed:15369820, PubMed:16787387, PubMed

    Polypeptides: All-trans-retinol dehydrogenase [NAD(+)] ADH7
  7. Target

    All-trans-retinol dehydrogenase [NAD(+)] ADH4

    go.drugbank.com/bio_entities/BE0000360
    TargetEnzymeHumans

    Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol (PubMed:17279314).

    Polypeptides: All-trans-retinol dehydrogenase [NAD(+)] ADH4
  8. Target

    TIR domain-containing adapter molecule 1

    go.drugbank.com/bio_entities/BE0016552
    TargetHumans

    Ligand binding to these receptors results in TRIF recruitment through its TIR domain (PubMed:12471095, PubMed:12539043, PubMed:14739303).

    Polypeptides: TIR domain-containing adapter molecule 1Synonyms: Proline-rich, vinculin and TIR domain-containing protein B, TIR domain-containing adapter protein inducing IFN-beta
  9. Target

    All-trans-retinol dehydrogenase [NAD(+)] ADH1B

    go.drugbank.com/bio_entities/BE0000400
    TargetEnzymeHumans

    Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal (PubMed:15369820) … In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal (PubMed:15369820, PubMed:16787387).

    Polypeptides: All-trans-retinol dehydrogenase [NAD(+)] ADH1B
  10. Target

    Immunoglobulin heavy variable 3-23

    go.drugbank.com/bio_entities/BE0004165
    TargetHumans

    V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...

    Synonyms: Ig heavy chain V-III region TIL