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Vitamin K-dependent protein S
go.drugbank.com/bio_entities/BE0000943TargetHumansAnticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis
Synonyms: PROSTrifunctional purine biosynthetic protein adenosine-3
go.drugbank.com/bio_entities/BE0000882TargetHumansTrifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway
Synonyms: PRGSLymphocyte activation gene 3 protein
go.drugbank.com/bio_entities/BE0010189TargetHumansInhibitory receptor on antigen activated T-cells (PubMed:20421648, PubMed:35761082, PubMed:7805750, PubMed:8647185). Delivers inhibitory signals upon binding to ligands, such as MHC class II, its main ligand present at the surface of ant...
Synonyms: LAG-3Ribose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001628TargetShigella flexneriCatalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Synonyms: PRIRibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0003268TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Synonyms: PRIRibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001557TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Synonyms: PRIMajor prion protein
go.drugbank.com/bio_entities/BE0001105TargetEnzymeHumansIts primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG...
Synonyms: PRIPLipoyl synthase, mitochondrial
go.drugbank.com/bio_entities/BE0002327TargetHumansCatalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated deri...
Synonyms: LASE3 ubiquitin-protein ligase pellino homolog 1
go.drugbank.com/bio_entities/BE0018269TargetHumansE3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:12496252, PubMed:17675297, PubMed:29883609, PubMed:30952868). Involved in the TLR and IL-1 signaling pathways via interaction wi...
Synonyms: PRISM