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Displaying results 1 - 10 of 804 in total
  1. Target

    Pepsin A-4

    go.drugbank.com/bio_entities/BE0012524
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-4Synonyms: Pepsinogen-4
  2. Target

    Leukotriene A-4 hydrolase

    go.drugbank.com/bio_entities/BE0001680
    TargetHumans

    Can utilize LTA5 less effectively as a substrate than LTA4, and produce LTB5 (PubMed:2996528). … addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a

    Polypeptides: Leukotriene A-4 hydrolaseSynonyms: Leukotriene A(4) hydrolase, LTA-4 hydrolase
  3. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0008383
    TargetStaphylococcus aureus

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  4. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000429
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  5. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000798
    TargetEscherichia coli (strain K12)

    MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation (PubMed:20921377).

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  6. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0003726
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  7. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    In the nervous system, also plays a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. … In addition to its role in axonal guidance plays a role in synaptic plasticity.

    Polypeptides: Ephrin type-A receptor 4
  8. Target

    Inositol polyphosphate-4-phosphatase type I A

    go.drugbank.com/bio_entities/BE0018619
    EnzymeHumans

    Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (PubMed:15716355, PubMed:20463662).

    Polypeptides: Inositol polyphosphate-4-phosphatase type I ASynonyms: Inositol polyphosphate 4-phosphatase type I, Type I inositol 3,4-bisphosphate 4-phosphatase
  9. Target

    Pleckstrin homology domain-containing family A member 4

    go.drugbank.com/bio_entities/BE0001278
    TargetHumans

    Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides

    Polypeptides: Pleckstrin homology domain-containing family A member 4Synonyms: PH domain-containing family A member 4
  10. Target

    Potassium voltage-gated channel subfamily A member 4

    go.drugbank.com/bio_entities/BE0004502
    TargetHumans

    Likewise, a heterotetrameric channel formed by KCNA1 and KCNA4 shows rapid inactivation (PubMed:17156368) … Homotetrameric KCNA4 forms a potassium channel that opens in response to membrane depolarization, followed by rapid spontaneous channel closure (PubMed:19912772, PubMed:8495559).

    Polypeptides: Potassium voltage-gated channel subfamily A member 4