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Apolipoprotein B-100
go.drugbank.com/bio_entities/BE0009908TargetHumansApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). … Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor
Polypeptides: Apolipoprotein B-100Synonyms: Apo B-100Protein S100-A1
go.drugbank.com/bio_entities/BE0001090TargetHumansSmall calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600). In response to an increase in intracellular Ca(2+) l...
Synonyms: S-100 protein alpha chain, S-100 protein subunit alphaProtein S100-B
go.drugbank.com/bio_entities/BE0001177TargetHumansSmall zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain (PubMed:20950652, PubMed:6487634). Weakly binds calcium but binds zinc very tightly-di...
Synonyms: S-100 protein beta chain, S-100 protein subunit betaVascular cell adhesion protein 1
go.drugbank.com/bio_entities/BE0001114TargetHumansCell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed:31310649). Acts as a major regulator of leukocyte adhesion to the endothe...
Synonyms: INCAM-100Splicing factor, proline- and glutamine-rich
go.drugbank.com/bio_entities/BE0008965TargetHumansDNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in s...
Synonyms: 100 kDa DNA-pairing protein, DNA-binding p52/p100 complex, 100 kDa subunitTransitional endoplasmic reticulum ATPase
go.drugbank.com/bio_entities/BE0004572TargetHumansNecessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to...
Synonyms: 15S Mg(2+)-ATPase p97 subunitApolipoprotein B receptor
go.drugbank.com/bio_entities/BE0005852TargetTransporterHumansMacrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL ...
Synonyms: Apolipoprotein B-100 receptorApolipoproteins
go.drugbank.com/bio_entities/BE0010065CarrierTargetHumansApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). … Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor
Polypeptides: Apolipoprotein B-100Synonyms: Apo B-100Cell adhesion molecule CEACAM5
go.drugbank.com/bio_entities/BE0004224TargetHumansCell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:10864933, PubMed:10910050, PubMed:2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryoni...
Synonyms: Meconium antigen 100