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Displaying results 1 - 10 of 423 in total
  1. Target

    5-oxoprolinase

    go.drugbank.com/bio_entities/BE0002268
    TargetEnzymeHumans

    Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate

    Polypeptides: 5-oxoprolinaseSynonyms: 5-OPase, 5-oxo-L-prolinase
  2. Target

    Cadherin-5

    go.drugbank.com/bio_entities/BE0003403
    TargetHumans

    Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (Pu...

    Polypeptides: Cadherin-5
  3. Target

    Frizzled-5

    go.drugbank.com/bio_entities/BE0014104
    TargetHumans

    Receptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By sim...

    Polypeptides: Frizzled-5Synonyms: Fz-5
  4. Target

    5'-nucleotidase

    go.drugbank.com/bio_entities/BE0001096
    TargetEnzymeHumans

    Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:22997138, PubMed:23142347, PubMed:24887587, PubMed:344...

    Polypeptides: 5'-nucleotidaseSynonyms: 5'-NT, 5'-deoxynucleotidase
  5. Target

    Interleukin-5

    go.drugbank.com/bio_entities/BE0001208
    TargetHumans

    Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276). Also acts on activated and resting ...

    Polypeptides: Interleukin-5Synonyms: IL-5
  6. Target

    Kallikrein-5

    go.drugbank.com/bio_entities/BE0010708
    TargetHumans

    May be involved in desquamation

    Polypeptides: Kallikrein-5
  7. Target

    Retinol dehydrogenase 5

    go.drugbank.com/bio_entities/BE0000570
    TargetEnzymeHumans

    Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:10588954, PubMed:11675386, PubMed:9115228, PubMed:9931293). Has no activity towards all-trans retinal (By...

    Polypeptides: Retinol dehydrogenase 5Synonyms: Short chain dehydrogenase/reductase family 9C member 5
  8. Target

    Peroxiredoxin-5, mitochondrial

    go.drugbank.com/bio_entities/BE0000907
    TargetEnzymeHumans

    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor o...

    Polypeptides: Peroxiredoxin-5, mitochondrialSynonyms: Thioredoxin-dependent peroxiredoxin 5
  9. Target

    5-aminolevulinate synthase

    go.drugbank.com/bio_entities/BE0002158
    TargetHumans

    Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.

    Polypeptides: 5-aminolevulinate synthaseSynonyms: 5-aminolevulinic acid synthase
  10. Target

    Integrin alpha-5

    go.drugbank.com/bio_entities/BE0008988
    TargetHumans

    Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands.

    Polypeptides: Integrin alpha-5Synonyms: VLA-5