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Displaying results 1 - 10 of 56 in total
  1. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutase
  2. Target

    Receptor for retinol uptake STRA6

    go.drugbank.com/bio_entities/BE0009879
    TransporterHumans

    Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid (PubMed:18316031). … Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein

    Polypeptides: Receptor for retinol uptake STRA6
  3. Target

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

    go.drugbank.com/bio_entities/BE0001300
    TargetHumans

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K

    Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
  4. Target

    Advanced glycation end product-specific receptor

    go.drugbank.com/bio_entities/BE0010032
    TransporterTargetHumans

    Protects cells from DNA replication stress by localizing to damaged replication forks where it stabilizes the MCM2-7 complex and promotes faithful progression of the replication fork (PubMed:36807739). … Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons (PubMed:19906677).

    Synonyms: Receptor for advanced glycation end products, Receptor for advanced glycosylation end products
  5. Target

    Chemotaxis protein CheA

    go.drugbank.com/bio_entities/BE0001431
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).

    Polypeptides: Chemotaxis protein CheA
  6. Target

    Calcium-dependent secretion activator 2

    go.drugbank.com/bio_entities/BE0008710
    TargetHumans

    Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development.

    Synonyms: Calcium-dependent activator protein for secretion 2
  7. Target

    Afadin

    go.drugbank.com/bio_entities/BE0004342
    TargetHumans

    Essential for the organization of adherens junctions (PubMed:30463011)

    Synonyms: ALL1-fused gene from chromosome 6 protein
  8. Target

    Bile salt-activated lipase

    go.drugbank.com/bio_entities/BE0004523
    TargetEnzymeHumans

    Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity).

    Polypeptides: Bile salt-activated lipaseSynonyms: Bile salt-stimulated lipase
  9. Target

    Bile salt hydrolase/transferase

    go.drugbank.com/bio_entities/BE0001392
    TargetClostridium perfringens (strain 13 / Type A)

    Shows a slight preference for taurine-conjugated bile acids as substrates (PubMed:7618863). … Acts as a bile salt hydrolase that catalyzes the deconjugation of glycine- and taurine-linked bile salts, which occurs naturally in the intestines of humans, releasing amino acid residues and deconjugated

    Polypeptides: Bile salt hydrolase/transferaseSynonyms: Bile salt hydrolase
  10. Target

    Hyaluronan mediated motility receptor

    go.drugbank.com/bio_entities/BE0004702
    TargetHumans

    Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs.

    Synonyms: Receptor for hyaluronan-mediated motility