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  1. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. … Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone.

    Synonyms: Paliperidone, PaliperidonaSalts: Paliperidone palmitate
  2. Pathway

    Paliperidone Serotonin Antagonist Action Pathway

    smpdb.ca/view/SMP0126597
    Drug action

    Paliperidone is the primary active metabolite of risperidone. … Paliperidone, by contrast, is predominantly excreted unchanged in the urine The mechanism of action of paliperidone is unknown but it is likely to act via a similar pathway to risperidone as second generation

    Drugs: Pyridoxal phosphate · Tryptophan · Sapropterin · Paliperidone · Calcium · Iron +1 more
  3. Pathway

    Paliperidone Dopamine Antagonist Action Pathway

    smpdb.ca/view/SMP0126592
    Drug action

    Paliperidone is the primary active metabolite of risperidone. … Paliperidone, by contrast, is predominantly excreted unchanged in the urine The mechanism of action of paliperidone is unknown but it is likely to act via a similar pathway to risperidone as second generation

    Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Dopamine · Levodopa · Paliperidone +2 more
  4. Indication

    Schizoaffective Disorders

    go.drugbank.com/conditions/DBCOND0033299
    Drugs: Paliperidone
  5. Pathway

    Risperidone Serotonin Antagonist Action Pathway

    smpdb.ca/view/SMP0126598
    Drug action

    Paliperidone is the primary active metabolite of risperidone. … Paliperidone, by contrast, is predominantly excreted unchanged in the urine. The major active metabolite, 9-hydroxyrisperidone, contributes to the pharmacological effects of this drug.

    Drugs: Pyridoxal phosphate · Tryptophan · Sapropterin · Risperidone · Paliperidone · Calcium +3 more
  6. Pathway

    Risperidone Dopamine Antagonist Action Pathway

    smpdb.ca/view/SMP0126599
    Drug action

    Paliperidone is the primary active metabolite of risperidone. … Paliperidone, by contrast, is predominantly excreted unchanged in the urine. The main route of risperidone metabolism is in the liver by the enzyme CYP2D6.

    Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Risperidone · Dopamine · Levodopa +4 more
  7. Indication

    Schizophrenias

    go.drugbank.com/conditions/DBCOND0033618
    Drugs: Aripiprazole · Aripiprazole lauroxil · Asenapine · Brexpiprazole · Cariprazine · Chlorpromazine +28 more