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Riboflavin
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
Flavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigationalFlavin mononucleotide (FMN), also known as riboflavin 5'-phosphate, is one of the two major coenzymes derived from [riboflavin] (vitamin B2) and is one of the principal forms in which dietary riboflavin … [L54226] In addition to its systemic use as a means of riboflavin supplementation, a topical ophthalmic preparation of FMN was approved by the FDA in October 2025 for use as a photoenhancer in epithelium-on
Salts: Riboflavin sodium phosphate, Riboflavin 5'-phosphate sodium anhydrousSynonyms: Riboflavin phosphate, riboflavin 5'-phosphateFlavin adenine dinucleotide
go.drugbank.com/drugs/DB03147ApprovedA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase.
Synonyms: Riboflavin 5'-adenosine diphosphate, adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate]Riboflavin tetrabutyrate
go.drugbank.com/drugs/DB14727InvestigationalSynonyms: Riboflavin tetrabutyrate, Riboflavin 2',3',4',5'-tetrabutyrateRiboflavin kinase
go.drugbank.com/bio_entities/BE0000370TargetHumansCatalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD.
Polypeptides: Riboflavin kinaseFunction: riboflavin kinase activityRiboflavin synthase
go.drugbank.com/bio_entities/BE0003327TargetEscherichia coli (strain K12)Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Polypeptides: Riboflavin synthaseFunction: riboflavin synthase activityRiboflavin biosynthesis protein
go.drugbank.com/bio_entities/BE0002551TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Polypeptides: Riboflavin biosynthesis proteinSolute carrier family 52, riboflavin transporter, member 3
go.drugbank.com/bio_entities/BE0019983TransporterHumansHumans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145) … Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino
Polypeptides: Solute carrier family 52, riboflavin transporter, member 3Synonyms: Riboflavin transporter 2Solute carrier family 52, riboflavin transporter, member 2
go.drugbank.com/bio_entities/BE0004841TargetTransporterHumansHumans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145). May also act as a receptor for 4-hydroxybutyrate (Probable) … Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino
Polypeptides: Solute carrier family 52, riboflavin transporter, member 2Synonyms: Riboflavin transporter 3