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Displaying results 1 - 10 of 432 in total
  1. Drug

    Simvastatin

    go.drugbank.com/drugs/DB00641
    ApprovedInvestigational

    Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_. … [A181087, A181406] Simvastatin and other drugs from the statin class of medications including [atorvastatin], [pravastatin], [rosuvastatin], [fluvastatin], and [lovastatin] are considered first-line

    Synonyms: Simvastatin, SimvastatinaMixtures: EZETIMIBE E SIMVASTATINA DOC GENERICI, EZETIMIBE E SIMVASTATINA DOC GENERICI
  2. Drug

    Acetyl simvastatin

    go.drugbank.com/drugs/DB14648
    Experimental

    Synonyms: Acetyl simvastatin, Simvastatin acetate
  3. Pathway

    Simvastatin Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174691
    Metabolic

    Metabolites of Simvastatin are predicted with biotransformer.

    Drugs: Simvastatin · Mesoheme
  4. Pathway

    Simvastatin Action Pathway

    smpdb.ca/view/SMP0000082
    Drug action

    Simvastatin, the methylated form of lovastatin, is an inactive lactone that is metabolized in vivo to β,δ-dihydroxy acid, its most potent metabolite. … The simvastatin hydroxy acid inhibits cholesterol synthesis via the mevalonate pathway by competitively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.

    Drugs: Cholecalciferol · ATP · Simvastatin · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 more
  5. Pathway

    Simvastatin Action Pathway (New)

    smpdb.ca/view/SMP0124578
    Drug action

    Reported side effects of Simvastatin include constipation, flatulence, dyspepsia (indigestion), abdominal pain, headache, and myalgia (muscle pain). … Simvastatin is a well-tolerated orally-administered synthetic statin that reduces total cholesterol levels, low-density lipoprotein (LDL)-cholesterol, triglyceride, and very-low-density lipoprotein (VLDL

    Drugs: Simvastatin · Calcium · Zinc · Cholesterol
  6. Drug

    Ezetimibe

    go.drugbank.com/drugs/DB00973
    ApprovedInvestigational

    Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in ...

    Mixtures: EZETIMIBE E SIMVASTATINA DOC GENERICI, EZETIMIBE E SIMVASTATINA DOC GENERICICategories: simvastatin and ezetimibe
  7. Drug

    Wheat bran

    go.drugbank.com/drugs/DB10685
    Approved

    Wheat bran allergenic extract is used in allergenic testing.

    Synonyms: Wheat branProducts: Wheat Bran
  8. Drug

    Rice bran oil

    go.drugbank.com/drugs/DB11293
    ApprovedInvestigational

    Rice bran oil is classified as an indirect additive used in food contact substances by the FDA. … The major constituents of rice bran oil include myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, and α-Linolenic acid.

    Synonyms: Rice bran oilProducts: essenHerb Rice Bran 90 Cleansing
  9. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and c...

    Mixtures: PINEAPPLE BRAND LOTION, AXE BRAND MEDICATED OILProducts: Band-aid Brand Anti-itch Gel, Band-aid Brand Anti-itch Spray
  10. Drug

    Rice bran

    go.drugbank.com/drugs/DB14361
    Approved

    Rice bran is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Rice bran, Rice Bran Wax