Displaying drugs 3526 - 3550 of 12485 in total
Streptomycin
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Zinc chloride
Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Description: … Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Taurolidine
Taurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid taurine.
It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal bacterial infections in patients with peritonitis. In November 2023, a catheter lock solution of...
Approved
Investigational
Matched Description: … It is a derivative of the amino acid [taurine]. ... It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal ... and Antifungal Drugs (LPAD pathway) for the prevention of catheter-related bloodstream infections in a …
Foreskin fibroblast (neonatal)
Foreskin fibroblast-like stromal cells (FDSCs) are progenitors isolated from human tissue that can differentiate into various cell types .
Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports wound healing .
Dermagraft has only...
Approved
Matched Description: … Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. ... Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports ... Dermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds …
Foreskin keratinocyte (neonatal)
Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes. The keratinocytes form a...
Approved
Matched Description: … Foreskin keratinocytes are a form of skin cells that are cultured as a skin cell replacement for wounds ... Keratinocytes are derived from neonatal foreskins and used to create a drug called _Apligraf_, a mixture ... To construct a "living" alternative, a dermal substitute based on collagen I gel was created with mesenchymal …
Dicyclomine
Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Description: … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... ,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a …
Tripelennamine
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
Approved
Vet approved
Matched Description: … A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. …
Streptococcus pneumoniae type 12f capsular polysaccharide antigen
Streptococcus pneumoniae type 12f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 12f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 12f capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 17f capsular polysaccharide antigen
Streptococcus pneumoniae type 17f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 17f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 17f capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 18c capsular polysaccharide antigen
Streptococcus pneumoniae type 18c capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 18c of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 18c capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 19f capsular polysaccharide antigen
Streptococcus pneumoniae type 19f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 19f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 19f capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 22f capsular polysaccharide antigen
Streptococcus pneumoniae type 22f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 22f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 22f capsular polysaccharide antigen is a vaccine that contains highly purified …
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Benserazide
When levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the blood and to various extracerebral tissues. This can result in a number of side effects like nausea, vomiting,...
Approved
Investigational
Matched Description: … When levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism ... into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the blood ... This can result in a number of side effects like nausea, vomiting, or even cardiac arrhythmias that may …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment ... Typically prescribed for the management of diabetes mellitus, insulin is a peptide hormone produced by …
Necitumumab
Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist. It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and...
Approved
Investigational
Matched Description: … functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a ... Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment …
Adenosine phosphate
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Description: … was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a …
Diphemanil
Approved
Vet approved
Withdrawn
Orthosiphon aristatus leaf
Approved
Experimental
Secretin human
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Description: … Although it is a gastrointestinal hormone, secretin is also considered as a neuropeptide hormone since ... Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Description: … Levomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound ... stability required for use as a supplement [A19276]. ... Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form …
Lanolin alcohols
Lanolin alcohols are a complex combination of organic alcohols obtained by the hydrolysis of lanolin. It is administered as an ointment base with topical insulin and has shown to be antagonistic to wound healing. It is commonly used in allergenic testing.
Approved
Experimental
Matched Description: … Lanolin alcohols are a complex combination of organic alcohols obtained by the hydrolysis of lanolin. …
Darbepoetin alfa
Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Lapatinib
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Description: … Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours ... Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor …
Displaying drugs 3526 - 3550 of 12485 in total