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Displaying drugs 3726 - 3750 of 11778 in total
Approved
Experimental
Perhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Approved
Investigational
Matched Description: … Perhexiline is a coronary vasodilator used especially for angina of effort. …
Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Description: … Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia ... It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor …
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … to a dimer and then to a monomer that is absorbed more rapidly after subcutaneous injection compared ... build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type …
C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a...
Approved
Matched Description: … human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction ... L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a
Clonostachys rosea f. rosea allergenic extract is used in allergenic testing.
Approved
Cephalosporium roseum allergenic extract is used in allergenic testing.
Approved
Honey is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Description: … drug with demonstrated safety and therapeutic efficacy in treating HCV genotype 3 without the need for co-administration ... Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Approved
Matched Description: … Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the ... Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography …
Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Salbutamol has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has...
Approved
Investigational
Matched Description: … Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment ... [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively …
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Description: … It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... A lignan found in podophyllin resin from the roots of podophyllum plants. …
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Description: … Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated ... Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and ... generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]),[A178084] dexlansoprazole has a
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Description: … Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a
Teclistamab is an IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug...
Approved
Investigational
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Description: … Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic …
Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Description: … Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. ... Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and ... Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), …
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Description: … Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against …
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and...
Approved
Investigational
Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Description: … Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging …
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Description: … to treat a variety of infections. ... First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used ... [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each …
Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human …
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also...
Approved
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Displaying drugs 3726 - 3750 of 11778 in total