Displaying drugs 4301 - 4325 of 11598 in total
Coagulin-B
Coagulin-B is an adeno-associated viral vector expressing human blood-coagulation Factor IX.[A259038, A259043] It was previously investigated for the treatment of hemophilia; however, the manufacturing company discontinued the Phase I trial in 2004, halting its further development and investigation.
Investigational
Niflumic acid
Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Experimental
Tenofovir
Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and...
Experimental
Investigational
Matched Description: … [A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the …
Methylmalonic Acid
A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem]
Experimental
Matched Description: … This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl ... CoA. ... A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. …
Denecimig
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Description: … Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9. …
Hypericin
Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
Investigational
Matched Categories: … Benz(a)Anthracenes …
Fazadinium bromide
Experimental
Matched Iupac: … -1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium dibromide ... 3-methyl-1-[(E)-2-{3-methyl-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium-1-yl}diazen-1-yl]-2-phenyl …
Minodronic acid
Investigational
Matched Iupac: … (1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosphonoethyl)phosphonic acid …
Alvespimycin
Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent. In comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic...
Investigational
Matched Description: … Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. …
Matched Categories: … HSP90 Heat-Shock Proteins …
Matched Categories: … HSP90 Heat-Shock Proteins …
Verucerfont
Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Investigational
Matched Iupac: … 4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a] …
ABBV-CLS-7262
Investigational
Hexobarbital
A barbiturate that is effective as a hypnotic and sedative.
Experimental
Matched Description: … A barbiturate that is effective as a hypnotic and sedative. …
SNX-2112
SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor.
Investigational
Matched Description: … SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor.[A253137] …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Ganetespib
Ganetespib is under investigation for the treatment of BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid Leukaemia, and Myelodysplastic Syndrome.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
(S)-camphor
(S)-camphor, or L(-)-Camphor, is a stereoisomer of DB01744, a bicyclic monoterpene known to potentiate both heat and cold sensations . (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and current inhibition . DB01744 is isolated from the wood of the camphor laurel tree, Cinnamomum camphora, and...
Experimental
Matched Description: … both heat and cold sensations [A33087]. ... by causing sensitization to heat and coolness to relieve minor muscle and joint pain [A33086]. ... (S)-camphor, or L(-)-Camphor, is a stereoisomer of [DB01744], a bicyclic monoterpene known to potentiate …
2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol
Experimental
BIIB021
BIIB021 has been investigated for the treatment of Tumors and Lymphoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Aluminium clofibrate
Experimental
TAK-475
TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been brought to market.
Investigational
Matched Description: … TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been …
Anagliptin
Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
Investigational
Matched Iupac: … N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine …
Indiplon
Indiplon has been used in trials studying the treatment of Insomnia and Depression.
Investigational
Matched Iupac: … N-methyl-N-{3-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}acetamide …
Edotecarin
Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. It is member of the class of compounds called indolocarbazoles.
Investigational
Matched Description: … Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. …
Displaying drugs 4301 - 4325 of 11598 in total