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Displaying drugs 5301 - 5325 of 11629 in total
Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Experimental
Investigational
Matched Description: … Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment …
Rezatomidine has been used in trials studying the treatment of Fibromyalgia, Cystitis, Interstitial, Irritable Bowel Syndrome, and Diabetic Neuropathy, Painful.
Investigational
Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).
Investigational
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Iupac: … phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a] …
Asoprisnil (J867) is a selective progesterone receptor modulator. It can be used to treat progesterone sensitive myomata.
Investigational
Matched Iupac: … phenyl}-1-methoxy-1-(methoxymethyl)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Asoprisnil (J867) is a selective progesterone receptor modulator. …
Experimental
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Experimental
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid …
Vet approved
Matched Iupac: … dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Aprindine is a cardiac depressant used in arrhythmias.
Experimental
Matched Description: … Aprindine is a cardiac depressant used in arrhythmias. …
Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Investigational
A spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly potent antiviral effects for HIV-1.
Investigational
Matched Description: … A spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly …
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Description: … ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic ... ADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors ... Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells …
Investigational
MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). This variant contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as PEGylation sites, and from which multiple undesired, naturally occurring lysines have been removed as compared to wild type human...
Investigational
Matched Description: … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). ... attached at the amino terminal end of the protein and at two internal lysine residues, while Neulasta has a
Matched Categories: … Compounds used in a research, industrial, or household setting …
Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.
Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tocotrienol has been investigated for the treatment of Cholesterol Lowering.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors).
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy Adult With Influenza Fever).
Investigational
Matched Description: … Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled …
Matched Categories: … Compounds used in a research, industrial, or household setting …
ACR-16 is under investigation by NeuroSearch. ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within Huntington’s disease, Parkinson’s disease and schizophrenia respectively. ACR-16 is a dopamine stabilizer. ACR-16 is also being...
Investigational
Matched Description: … ACR-16 is a dopamine stabilizer. ... ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled …
ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic lateral sclerosis (ALS). It is being developed by Avicena Group, Inc.
Investigational
Matched Description: … ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic …
AI-128 is the first human demonstration of sustained release drug administration in the lung. AI-128 consists of slowly dissolving microspheres designed to control where drug particles go in the lung and how quickly they release their drug.
Investigational
AV-101 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Investigational
Investigational
Investigational
Displaying drugs 5301 - 5325 of 11629 in total