Displaying drugs 676 - 700 of 15298 in total
Azatadine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
Matched Description: … Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on …
Matched Mixtures name: … XL-3 VR ... XL-3 XTRA …
Matched Categories: … Antihistamines for Systemic Use …
Matched Description: … Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on …
Matched Mixtures name: … XL-3 VR ... XL-3 XTRA …
Matched Categories: … Antihistamines for Systemic Use …
Tubocurarine
Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera Chondrodendron and Strychnos....
Approved
Matched Synonyms: … 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium …
Matched Description: … [A216008] Tubocurarine is a benzylisoquinoline derivative and shares this structural backbone with a ... [A216028] It was first isolated by Harold King in 1935 and was used clinically to induce neuromuscular ... non-depolarizing neuromuscular blockers, such as [rocuronium], have largely replaced the use of tubocurarine in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … [A216008] Tubocurarine is a benzylisoquinoline derivative and shares this structural backbone with a ... [A216028] It was first isolated by Harold King in 1935 and was used clinically to induce neuromuscular ... non-depolarizing neuromuscular blockers, such as [rocuronium], have largely replaced the use of tubocurarine in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tecovirimat
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. It is effective against all orthopoxviruses,...
Approved
Investigational
Matched Description: … [A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002 ... [A35133] It is effective against all orthopoxviruses, including vaccinia, cowpox, ectromelia, rabbitpox ... eradicated in 1980. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Ambrosia artemisiifolia pollen
Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Description: … Ambrosia artemisiifolia pollen is mainly used in allergenic testing. …
Matched Mixtures name: … 3-ragweed Mix, Giant/short/western Pollen …
Matched Mixtures name: … 3-ragweed Mix, Giant/short/western Pollen …
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration …
Phalaris arundinacea pollen
Phalaris arundinacea pollen is the pollen of the Phalaris arundinacea plant. Phalaris arundinacea pollen is mainly used in allergenic testing.
Approved
Matched Description: … Phalaris arundinacea pollen is mainly used in allergenic testing. …
Meclizine
Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Iupac: … 1-[(4-chlorophenyl)(phenyl)methyl]-4-[(3-methylphenyl)methyl]piperazine …
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular ... [L6760] Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets …
Matched Salts cas: … 31884-77-2 …
Matched Categories: … Antihistamines for Systemic Use …
Matched Products: … Wal-Dram 2 Quick-Dissolving ... Motion Sickness All Day Less Drowsy …
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular ... [L6760] Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets …
Matched Salts cas: … 31884-77-2 …
Matched Categories: … Antihistamines for Systemic Use …
Matched Products: … Wal-Dram 2 Quick-Dissolving ... Motion Sickness All Day Less Drowsy …
Amaranthus palmeri pollen
Amaranthus palmeri pollen is the pollen of the Amaranthus palmeri plant. Amaranthus palmeri pollen is mainly used in allergenic testing.
Approved
Matched Description: … Amaranthus palmeri pollen is mainly used in allergenic testing. …
Ciclopirox
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Synonyms: … 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a ... synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. ... In particular, the agent is especially effective in treating Tinea versicolor. …
Matched Salts cas: … 41621-49-2 …
Matched Mixtures name: … Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox Olamine 1% / Salicylic Acid 2% ... Ciclopirox 3% / Itraconazole 5% / Urea 20% …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Products: … Ciclopirox 3% ... NIBULEN 80 MG/G TIRNAK CILASI SETİ, 3 G ... SİROKSİL 80 MG/G TIRNAK CİLASI SETİ, 3 G …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a ... synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. ... In particular, the agent is especially effective in treating Tinea versicolor. …
Matched Salts cas: … 41621-49-2 …
Matched Mixtures name: … Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox Olamine 1% / Salicylic Acid 2% ... Ciclopirox 3% / Itraconazole 5% / Urea 20% …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Products: … Ciclopirox 3% ... NIBULEN 80 MG/G TIRNAK CILASI SETİ, 3 G ... SİROKSİL 80 MG/G TIRNAK CİLASI SETİ, 3 G …
L-Lactic acid
Approved
Experimental
Matched Synonyms: … (S)-2-hydroxypropanoic acid ... (S)-2-hydroxypropionic acid …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Mixtures name: … Prismasol 2 …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Mixtures name: … Prismasol 2 …
Ascorbic acid
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Synonyms: … Vitamin C ... Vitamina C …
Matched Iupac: … (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one …
Matched Description: … Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic ... A six carbon compound related to glucose. ... Vitamin C is considered an antioxidant. …
Matched Mixtures name: … Webber E Plus 3 Cap ... Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge ... Vitamin E + 3 (extra Strength) …
Matched Categories: … Compounds used in a research, industrial, or household setting ... ascorbic acid (vit C) ... Vitamin C and analogues ... ascorbic acid (vit C) and calcium …
Matched Products: … All Natural Source Juicy Orange Vitamin C ... Formula # 2 Pwr 15mg/g ... Vitamine C 500 A L'orange …
Matched Iupac: … (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one …
Matched Description: … Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic ... A six carbon compound related to glucose. ... Vitamin C is considered an antioxidant. …
Matched Mixtures name: … Webber E Plus 3 Cap ... Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge ... Vitamin E + 3 (extra Strength) …
Matched Categories: … Compounds used in a research, industrial, or household setting ... ascorbic acid (vit C) ... Vitamin C and analogues ... ascorbic acid (vit C) and calcium …
Matched Products: … All Natural Source Juicy Orange Vitamin C ... Formula # 2 Pwr 15mg/g ... Vitamine C 500 A L'orange …
Strontium ranelate
Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Iupac: … distrontium(2+) ion 5-[bis(carboxylatomethyl)amino]-3-(carboxylatomethyl)-4-cyanothiophene-2-carboxylate …
Matched Description: … 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an ... Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) ... It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe …
Matched Mixtures name: … FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET ... FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADET …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … PROTOS Granules for Oral Suspension 2g ... DIOSS 2 G EFERVESAN TABLET, 56 ADET ... BONCURE 2 G EFERVESAN TABLET, 56 ADET …
Matched Description: … 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an ... Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) ... It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe …
Matched Mixtures name: … FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET ... FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADET …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … PROTOS Granules for Oral Suspension 2g ... DIOSS 2 G EFERVESAN TABLET, 56 ADET ... BONCURE 2 G EFERVESAN TABLET, 56 ADET …
Salix nigra bark
Salix nigra bark allergenic extract is used in allergenic testing.
Approved
Matched Description: … Salix nigra bark allergenic extract is used in allergenic testing. …
Rumex crispus top
Rumex crispus top allergenic extract is used in allergenic testing.
Approved
Matched Description: … Rumex crispus top allergenic extract is used in allergenic testing. …
Solidago canadensis pollen
Solidago canadensis pollen is the pollen of the Solidago canadensis plant. Solidago canadensis pollen is mainly used in allergenic testing.
Approved
Matched Description: … Solidago canadensis pollen is mainly used in allergenic testing. …
Vinorelbine
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC .
It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Iupac: … ethyl-4-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3( …
Matched Description: … It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. ... It is a third-generation vinca alkaloid. ... a strong influence of genetics on the clearance of this drug [L2002]. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Vinorelbine Tartrate for Injection …
Matched Description: … It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. ... It is a third-generation vinca alkaloid. ... a strong influence of genetics on the clearance of this drug [L2002]. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Vinorelbine Tartrate for Injection …
Poa compressa pollen
Poa compressa pollen is the pollen of the Poa compressa plant. Poa compressa pollen is mainly used in allergenic testing.
Approved
Matched Description: … Poa compressa pollen is mainly used in allergenic testing. …
Trofinetide
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … ), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor ... [A258438] Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[ ... Trofinetide is a novel synthetic analog of [glypromate], also known as glycine–proline–glutamate (GPE …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … ), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor ... [A258438] Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[ ... Trofinetide is a novel synthetic analog of [glypromate], also known as glycine–proline–glutamate (GPE …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Description: … -2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma ... It is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin ... Current strategies for treatment include immunotherapy with drugs such as dinutuximab to target surviving …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures. ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies …
Quercus dumosa pollen
Quercus dumosa pollen is the pollen of the Quercus dumosa plant. Quercus dumosa pollen is mainly used in allergenic testing.
Approved
Matched Description: … Quercus dumosa pollen is mainly used in allergenic testing. …
Tildrakizumab
Tildrakizumab is a high-affinity, humanized, IgG1 κ antibody targeting interleukin 23 p19 that shows promise in the evolution of treatment strategy in chronic plaque psoriasis .
The Food and Drug Administration (FDA) approved ILUMYA (tildrakizumab-asmn) for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy...
Approved
Investigational
Matched Description: … with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy in ... promise in the evolution of treatment strategy in chronic plaque psoriasis [A32255]. ... The Food and Drug Administration (FDA) approved ILUMYA (tildrakizumab-asmn) for the treatment of adults …
Gadobenic acid
Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Iupac: … gadolinium(3+) ion 4-carboxy-8,11-bis(carboxylatomethyl)-5-(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan …
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... useful contrast agent for liver MRI. ... contrast agent (GBCA) used primarily for MR imaging of the liver. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... useful contrast agent for liver MRI. ... contrast agent (GBCA) used primarily for MR imaging of the liver. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine ... 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts cas: … 894-71-3 …
Matched Categories: … Antidepressive Agents Indicated for Depression ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts cas: … 894-71-3 …
Matched Categories: … Antidepressive Agents Indicated for Depression ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Displaying drugs 676 - 700 of 15298 in total