Displaying drugs 801 - 825 of 11650 in total
Isosorbide dinitrate
A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Approved
Investigational
Matched Description: … A vasodilator used in the treatment of angina pectoris. ... Its actions are similar to nitroglycerin but with a slower onset of action. …
Phenylalanine
Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Approved
Investigational
Nutraceutical
Matched Description: … Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin …
Medium-chain triglycerides
Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms. MCTs are found in natural foods, such as coconut oil, palm kernel oil, and raw coconut meat. In the body, MCTs are broken down into...
Approved
Matched Description: … Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids ... acids, which are directly absorbed into the blood stream and transported to the target organs to exert a ... [A246688] MCTs are used in parenteral nutrition therapy: they serve as a source of calories and essential …
Amaranthus tuberculatus pollen
Amaranthus tuberculatus pollen allergenic extract is used in allergenic testing.
Approved
Betrixaban
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Description: … Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible ... Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable …
Cidofovir
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Colesevelam
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is a bile acid sequestrant. …
Dihydroergocristine
Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Matched Description: … [L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed …
Elivaldogene autotemcel
Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy, an X-linked genetic disorder characterized by missing or non-functional ABCD1 gene that codes for ALDP. ALDP is a key protein that normally...
Approved
Matched Description: … Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. ... [A243691] ALDP is a key protein that normally breaks down fatty substances in the body called very long-chain ... Gene therapy with autologous hematopoietic stem cells was introduced and investigated as a possible treatment …
Atracurium besylate
A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
Approved
Matched Description: … A non-depolarizing neuromuscular blocking agent with short duration of action. …
Valaciclovir
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … It is a member of the purine (guanine) nucleoside analog drug class [F3949]. ... Genital herpes is a frequently diagnosed sexually transmitted disease which currently affects more than …
Escitalopram
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Categories: … Monoamine Oxidase A Substrates …
Halcinonide
Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc. Research suggests that clobetasol propionate demonstrates superior pharmacologic efficacy in the treatment of...
Approved
Investigational
Withdrawn
Matched Description: … of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. ... Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations …
Nicorandil
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Description: … It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by ... Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane …
Sodium sulfate
Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate...
Approved
Vet approved
Matched Description: … Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of …
Lebrikizumab
Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared tralokinumab.[A262874,A262879]
On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a body weight...
Approved
Investigational
Matched Description: … Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared [tralokinumab ... treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a …
Propiverine
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) .
Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the...
Approved
Investigational
Matched Description: … Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms ... OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents ... Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency …
Anti-inhibitor coagulant complex
Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Indapamide
The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … [A204134,A204161]
Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide ... [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium ... [A204155]
Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension …
Iva axillaris pollen
Iva axillaris pollen is the pollen of the Iva axillaris plant. Iva axillaris pollen is mainly used in allergenic testing.
Approved
Apiospora montagnei
Apiospora montagnei is a fungus which can provoke allergic reactions. Apiospora montagnei extract is used in allergenic testing.
Approved
Matched Description: … Apiospora montagnei is a fungus which can provoke allergic reactions. …
Potassium aspartate
Approved
Experimental
Pyrophosphoric acid
Approved
Experimental
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
Displaying drugs 801 - 825 of 11650 in total