Displaying drugs 10751 - 10775 of 11741 in total
BI-765063
BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα).
Investigational
Matched Description: … BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα). …
NXC680
NXC680 is a small molecule under investigation for the treatment of idiopathic pulmonary fibrosis (IPF).
Investigational
Matched Description: … NXC680 is a small molecule under investigation for the treatment of idiopathic pulmonary fibrosis (IPF …
IMC-1C11
IMC-1C11 is an anti-angiogenesis agent. It is a chimeric anti-kinase insert domain-containing receptor (KDR) antibody that blocks VEGFR-KDR interaction and inhibits VEGFR-induced endothelial cell proliferation. IMC-1C11 is used for treatment of patients with liver metastases from colorectal carcinoma.
Investigational
Matched Description: … It is a chimeric anti-kinase insert domain-containing receptor (KDR) antibody that blocks VEGFR-KDR interaction …
MLN2222
MLN2222 is a novel, proprietary recombinant protein that blocks both the C3 and C5 convertases, which are essential components of the complement activation pathway.
Investigational
Matched Description: … MLN2222 is a novel, proprietary recombinant protein that blocks both the C3 and C5 convertases, which …
Gallium maltolate
Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone disease and cancer.
Investigational
Renzapride
Renzapride is currently in Phase III clinical development in the United States for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). It has been suggested that renzapride is effective in the treatment of irritable bowel syndrome with alternating stool pattern. It is being developed by Alizyme of the UK.
Investigational
Cinolazepam
Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
Experimental
Matched Description: … Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle …
Farletuzumab
Farletuzumab (MORAb-003) is a fully humanized monoclonal antibody against the folate receptor alpha, for the potential treatment of epithelial ovarian cancer.
Investigational
Matched Description: … Farletuzumab (MORAb-003) is a fully humanized monoclonal antibody against the folate receptor alpha, …
5,7,2′-trihydroxy-6,8-dimethoxyflavone
5,7,2′-trihydroxy-6,8-dimethoxyflavone (K36) is a high-affinity, naturally occurring flavonoid derivative isolated from the medicinal herb Scutellaria baicalensis Georgi .
Experimental
Matched Description: … 5,7,2′-trihydroxy-6,8-dimethoxyflavone (K36) is a high-affinity, naturally occurring flavonoid derivative …
Maclura tricuspidata whole
Maclura tricuspidata whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Maclura tricuspidata whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Nardostachys chinensis whole
Nardostachys chinensis whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Nardostachys chinensis whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Tribulus terrestris fruit
Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
Juglans regia shell
Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. …
Calendula officinalis whole
Calendula officinalis whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Calendula officinalis whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Ilex paraguariensis leaf
Ilex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Ilex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Morinidazole
Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis).
Investigational
Matched Description: … Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and …
Voruciclib
Voruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
Investigational
Matched Description: … Voruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects …
TEL540-548
TEL540-548 is a recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT).
Investigational
Matched Description: … TEL540-548 is a recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase …
Ilomastat
Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.
Experimental
Matched Description: … Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor. …
Glibornuride
Glibornuride is a sulfonylurea-type anti-diabetic drug.
Investigational
Withdrawn
Matched Description: … Glibornuride is a sulfonylurea-type anti-diabetic drug. …
Bamifylline
Bamifylline is a selective A1 adenosine receptor antagonist.
Experimental
Matched Description: … Bamifylline is a selective A1 adenosine receptor antagonist. …
Protego-PD
Protego-PD is a post-delivery placental extract.
Investigational
Matched Description: … Protego-PD is a post-delivery placental extract. …
XL281
XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway. Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer. XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which...
Investigational
Matched Description: … XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway ... XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated …
PSN9301
PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for...
Investigational
Matched Description: … PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical …
TM30339
TM30339 is an analogue of the natural hormone Pancreatic Polypeptide (PP), which is released in connection with meals. TM30339 works through the same receptor as the natural satiety hormone, Pancreatic Polypeptide (PP), but TM30339 has improved properties compared with PP. TM30339 thus imitates a natural mechanism, a satiety signal from...
Investigational
Matched Description: … TM30339 thus imitates a natural mechanism, a satiety signal from the gastrointestinal system involved …
Displaying drugs 10751 - 10775 of 11741 in total