Displaying drugs 11826 - 11850 of 12714 in total
Asimadoline
Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It has shown encouraging clinical efficacy for the treatment of...
Investigational
Matched Iupac: … N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methyl-2,2-diphenylacetamide …
Matched Description: … Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. ... Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt ... It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients …
Matched Description: … Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. ... Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt ... It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients …
Ginkgolide A
Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Nutraceutical
Matched Synonyms: … Ginkgolide-A …
Matched Name: … Ginkgolide A …
Matched Description: … Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the ... Shows potential in a wide variety of inflammatory and immunological disorders. …
Matched Name: … Ginkgolide A …
Matched Description: … Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the ... Shows potential in a wide variety of inflammatory and immunological disorders. …
Avagacestat
Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease.
Investigational
Matched Iupac: … (2R)-5,5,5-trifluoro-2-(N-{[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl}4-chlorobenzenesulfonamido …
Atabecestat
Atabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates).
Investigational
Matched Iupac: … N-{3-[(4S)-2-amino-4-methyl-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide …
Matched Description: … Atabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 …
Matched Description: … Atabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 …
Acebilustat
Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).
Investigational
Matched Iupac: … 4-{[(1S,4S)-5-({4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl}methyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl …
Ursolic acid
Experimental
AZD8529
AZD8529 is under investigation in clinical trial NCT00921804 (Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia Patients).
Investigational
Matched Iupac: … 7-methyl-5-{3-[(piperazin-1-yl)methyl]-1,2,4-oxadiazol-5-yl}-2-{[4-(trifluoromethoxy)phenyl]methyl}-2,3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Astegolimab
Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Description: … Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
Avdoralimab
Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection).
Investigational
Matched Description: … clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 …
Alomfilimab
Alomfilimab is under investigation in clinical trial NCT03829501 (Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer).
Investigational
Ampiroxicam
Investigational
Matched Iupac: … ethyl 1-({2-methyl-1,1-dioxo-3-[(pyridin-2-yl)carbamoyl]-2H-1lambda6,2-benzothiazin-4-yl}oxy)ethyl carbonate …
APC8020
Investigational
ABX1100
ABX1100 is an investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 (Gys1), an enzyme that is responsible for glycogen synthesis in the muscle. It was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.
Investigational
Lauryl alcohol diphosphonic acid
Experimental
Alpha-Adenosine Monophosphate
Experimental
Matched Iupac: … {[(2R,3S,4R,5S)-5-(6-amino-7H-purin-7-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Imexon
Imexon is currently being studied for the treatment of pancreatic, lung, breast, prostate, melanoma, and multiple myeloma cancers. It belongs to the family of drugs called cyanoaziridine derivatives. Also called Amplimexon. Imexon is a cyanoaziridine derivative.
Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane...
Investigational
Matched Iupac: … 4-amino-1,3-diazabicyclo[3.1.0]hex-3-en-2-one …
Matched Description: … and cytochrome C, leading to apoptosis. ... Imexon is a cyanoaziridine derivative. ... Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane potential …
Matched Description: … and cytochrome C, leading to apoptosis. ... Imexon is a cyanoaziridine derivative. ... Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane potential …
SOT-107
SOT-107 is a drug that is a combination of a protein called transferrin and a poison called diphtheria toxin. This drug treat for a type of brain cancer called a high grade glioma brain tumour. About half of all brain tumours are gliomas.
Investigational
Matched Description: … SOT-107 is a drug that is a combination of a protein called transferrin and a poison called diphtheria ... This drug treat for a type of brain cancer called a high grade glioma brain tumour. …
Sodium dichloroacetate
Investigational
Myrtecaine
Experimental
Matched Iupac: … (2-{2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethoxy}ethyl)diethylamine …
Cordycepin Triphosphate
Experimental
Matched Iupac: … ({[({[(2S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dipyrromethane Cofactor
Experimental
Matched Iupac: … 3-(5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol ... -3-yl)propanoic acid …
Obecabtagene autoleucel
Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy.
Investigational
Alpha-Methyl-N-Acetyl-D-Glucosamine
Experimental
Matched Iupac: … N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-methoxyoxan-3-yl]acetamide …
Recombinant human arylsulfatase A
Investigational
Matched Synonyms: … Recombinant human arylsulfatase A ... Recombinant human arylsulphatase A …
Matched Name: … Recombinant human arylsulfatase A …
Matched Name: … Recombinant human arylsulfatase A …
Displaying drugs 11826 - 11850 of 12714 in total