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Displaying drugs 3376 - 3400 of 3929 in total

CPG-52852

852A has been used in trials studying the treatment of Melanoma, Neoplasms, Breast Cancer, Ovarian Cancer, and Cervical Cancer, among others.
Investigational
Matched Synonyms: … N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide …
Matched Iupac: … N-(4-{4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl}butyl)methanesulfonamide …

Reloxaliase

Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from Bacillus Subtilis. Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria).
Investigational

Exisulind

Investigational
Matched Synonyms: … 5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …

Lintuzumab satetraxetan AC-225

Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Investigational

Pagibaximab

Investigational

Prasterone sulfate

DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Iupac: … [(3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-oxo-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …

Tapencarium

Investigational
Matched Synonyms: … 5-[3,6-dibromo-9H-carbazol-9-yl]-N,N,N-trimethylpentan-1-aminium chloride …

Alidornase alfa

Investigational

Trotabresib

Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
Investigational
Matched Synonyms: … 4-(2-(cyclopropylmethoxy)-5-methylsulfonylphenyl)-2-methylisoquinolin-1-one ... 1(2h)-isoquinolinone, 4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl)-2-methyl- …

Cemsidomide

Investigational
Matched Synonyms: … (3s)-3-(6-((4-(morpholin-4-ylmethyl)phenyl)methyl)-2-oxobenzo(cd)indol-1-yl)piperidine-2,6-dione ... 2,6-piperidinedione, 3-(6-((4-(4-morpholinylmethyl)phenyl)methyl)-2-oxobenz(cd)indol-1(2h)-yl)-, (3s) …
Matched Iupac: … (3S)-3-[9-({4-[(morpholin-4-yl)methyl]phenyl}methyl)-3-oxo-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(11), …

Tepilamide fumarate

Investigational
Matched Synonyms: … 2-butenedioic acid (2e)-, 1-(2-(diethylamino)-2-oxoethyl) 4-methyl ester …

Verpasep caltespen

Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational

TP-3654

Investigational

Cantuzumab mertansine

Investigational
Matched Synonyms: … oxopropyl)maytansine (1:4) ... oxopropyl)maytansine (1:4) ... human-mouse monoclonal c242 light chain, dimer, compound with n(sup 2')-deacetyl-n(sup 2')-(3-mercapto-1- …

Coronavirus-Like Particle COVID-19 Vaccine

The Coronavirus-Like Particle COVID-19 Vaccine is in development and testing through Meidcago in Quebec City, Canada. The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection. VLPs are thought to have multiple mechanisms involving the...
Investigational
Matched Description: … A Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity …

Talditercept alfa

Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational

Ovemotide

Ovemotide is under investigation in clinical trial NCT00357461 (Ipilimumab With or Without Vaccine Therapy in Treating Patients With Previously Treated Stage IV Melanoma).
Investigational
Matched Synonyms: … MART-1:26-35(27L) peptide …

Tilavonemab

Investigational

RP-72

Investigational
Matched Synonyms: … CXC chemokine receptor types 1 and 2 inhibitor RP72 …

Belrestotug

Belrestotug is under investigation in clinical trial NCT05565378 (A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/metastatic Non-small-cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit) (human monoclonal eos884448 .gamma.1-chain), disulfide …

Quaratusugene ozeplasmid

Quaratusugene ozeplasmid is under investigation in clinical trial NCT05062980 (Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-small Lung Cancer).
Investigational

2-octyl cyanoacrylate

Dermabond has been investigated for the basic science of Wound Healing.
Investigational
Matched Synonyms: … 1-methylheptyl cyanoacrylate …

Pemtumomab

Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Synonyms: … Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 …
Matched Description: … It targets the mucin 1 (MUC1) protein. …

CMG901

CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational

Ethoxzolamide

Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 3376 - 3400 of 3929 in total