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Displaying drugs 3501 - 3525 of 4208 in total

Chiglitazar

Chiglitazar is under investigation in clinical trial NCT06125587 (Chiglitazar/metformin in Non-obese Women With PCOS).
Investigational
Matched Synonyms: … (2s)-3-(4-(2-carbazol-9-ylethoxy)phenyl)-2-(2-(4-fluorobenzoyl)anilino)propanoic acid ... O-(2-(9h-carbazol-9-yl)ethyl)-n-(2-(4-fluorobenzoyl)phenyl)-l-tyrosine ... L-tyrosine, o-(2-(9h-carbazol-9-yl)ethyl)-n-(2-(4-fluorobenzoyl)phenyl)- …

Pyrifazimine

Pyrifazimine is under investigation in clinical trial NCT04670120 (Early Bactericidal Activity Safety Pulmonary Tuberculosis Pyrifazimine (TBI-166)).
Investigational
Matched Synonyms: … 2-PHENAZINAMINE, 3,5-DIHYDRO-3-((4-METHOXYCYCLOHEXYL)IMINO)-N-(2-METHOXY-3-PYRIDINYL)-5-(4-(TRIFLUOROMETHOXY …

Torapsel

Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury.
Investigational
Matched Synonyms: … 42-89-GLYCOPROTEIN (HUMAN CLONE PMT21:PL85 P-SELECTIN GLYCOPROTEIN LIGAND-1) FUSION PROTEIN WITH IMMUNOGLOBULIN …

Icrucumab

Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).
Investigational

Seladelpar

Seladelpar (MBX-8025) has been used in trials studying the treatment of Hyperlipidemia.
Investigational
Matched Iupac: … 2-(4-{[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl}-2-methylphenoxy)acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BNT162a1 SARS-CoV-2 Vaccine

BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.[L15002, L15007] BNT162a1 is undergoing evaluation in clinical trials in both the USA (NCT04368728)...
Investigational

4-demethyl-4-cholesteryloxycarbonylpenclomedine

4-demethyl-4-cholesteryloxycarbonylpenclomedine is under investigation in clinical trial NCT01048008 (Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer).
Investigational
Matched Synonyms: … 4-DEMETHYLCHOLESTERYLOXYCARBONYLPENCLOMEDINE …
Matched Name: … 4-demethyl-4-cholesteryloxycarbonylpenclomedine …
Matched Iupac: … (1R,3aS,3bS,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H,8H ... 9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl 3,5-dichloro-2-methoxy-6-(trichloromethyl)pyridin-4- …
Matched Description: … 4-demethyl-4-cholesteryloxycarbonylpenclomedine is under investigation in clinical trial NCT01048008 ... (Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer …

Azodicarbonamide

Investigational

Dolastatin 10

Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Iupac: … -4-yl]-N,3-dimethylbutanamide ... -2-methyl-2-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]carbamoyl}ethyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan ... (2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N-[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy …

IL15-NK Cell

Natural killer (NK) cells can be incubated with ‘feeder cells’ expressing certain cytokines prior to maturation to enhance their activity. In particular, incubation with IL-15 allows NK cells to lyse a broad range of fresh and cultured tumor targets that the cell is not normally sensitive to.
Investigational

ZY19489

Investigational
Matched Iupac: … -1-yl]pyrimidine-2,4-diamine ... N2-(4-cyclopropyl-5-fluoro-6-methylpyridin-2-yl)-N4-(1,5-dimethyl-1H-pyrazol-3-yl)-5-[(3R)-3,4-dimethylpiperazin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Peptide YY (1-36)

Investigational
Matched Synonyms: … Peptide YY human (1-36) …
Matched Name: … Peptide YY (1-36) …

ISA101b

ISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.
Investigational

Cardiotrophin 1

Investigational
Matched Synonyms: … CT-1 ... Cardiotrophin-1 ... Protein cardiotrophin (human isoform 1) …
Matched Name: … Cardiotrophin 1 …

G17DT Immunogen

G17DT Immunogen is a vaccine that neutralizes gastrin-17, a hormone required for the growth of a number of cancers of the gastrointestinal tract. It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine. It is also in a phase II/III trial for...
Investigational

MMDA

MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Iupac: … 1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine …

Ananain

Investigational

Grn163l

GRN163L is a novel anti-cancer drug. It has been characterized preclinically and shown to inhibit telomerase in human tumor cells of many cancer types (including lung, breast, prostate, liver, and early stage of human breast cancer), in both cell culture systems and animal models. Study of this drug shows the...
Investigational

HY10275

HY10275 is a novel compound specifically designed to modulate two key neurobiological mechanisms that interfere with the sleeping process. HY10275 is highly selective for histamine H1 and serotonin 5HT2a, two chemical receptors that are known to impact the ability to fall asleep and stay asleep. HY10275 was rationally designed to...
Investigational

CMLVAX100

CMLVAX100 is a vaccine targeting the BCR-ABL-derived p210 fusion protein which reduces residual disease in some patients with chronic myeloid leukemia. It is developed by Breakthrough Therapeutics and has completed phase I of its clinical trial.
Investigational

Alovudine F-18

Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).
Investigational
Matched Iupac: … 1-[(2R,4S,5R)-4-(¹⁸F)fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …

NB-124 sulfate

Investigational
Matched Synonyms: … -d-gluco-heptopyranosyl-(1->4))-2-deoxy-, sulfate ... -d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha. …
Matched Iupac: … (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1S)-1-aminoethyl]-3,4 ... -dihydroxyoxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol; sulfuric acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

SYNB1353

SYNB1353 is a strain of the probiotic bacteria Escherichia coli (E. coli) type Nissle and an engineered probiotic drug. Developed by Synlogic Operating Company, Inc., SYNB1353 is being investigated for the treatment of homocystinuria. It is designed to consume methionine in the gastrointestinal tract to prevent its absorption and conversion...
Investigational

Axomadol

Axomadol is under investigation in clinical trial NCT01043263 (Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain).
Investigational
Matched Iupac: … (1S,3S,6S)-6-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexane-1,3-diol …

BNT162b1 SARS-CoV-2 Vaccine

BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin...
Investigational
Matched Description: … [L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding …
Displaying drugs 3501 - 3525 of 4208 in total