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Displaying drugs 4126 - 4150 of 4568 in total

Fenthion

Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase...
Vet approved
Matched Synonyms: … 4-methylmercapto-3-Methylphenyl dimethyl thiophosphate ... O,O-Dimethyl O-[3-methyl-4-(methylsulfanyl)phenyl] thiophosphate ... O,O-Dimethyl-O-4-(methylmercapto)-3-methylphenyl thiophosphate …
Matched Iupac: … O,O-dimethyl O-3-methyl-4-(methylsulfanyl)phenyl phosphorothioate …

Volrubigene ralaparvovec

Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational

Ulenistamab

Investigational
Matched Synonyms: … (human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal pbp1510 .gamma.1- …

AZD-0424

AZD0424 has been used in trials studying the treatment of Advanced Solid Tumours.
Investigational
Matched Iupac: … 1-[4-(2-{[4-({6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-yl}amino)-5-(propan-2-yloxy)quinazolin-7-yl]oxy ... }ethyl)piperazin-1-yl]ethan-1-one …

Lifirafenib

Lifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).
Investigational
Matched Iupac: … 5-{[(2R,3R,4S)-3-[6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]-5-oxatricyclo[4.4.0.0^{2,4}]deca-1(6), …

Pidnarulex

Investigational
Matched Iupac: … 4-(4-methyl-1,4-diazepan-1-yl)-N-[(5-methylpyrazin-2-yl)methyl]-8-oxo-11-thia-1,3-diazatetracyclo[8.7.0.0 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cethromycin

Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6-linked aromatic ring system. Cethromycin represents a joint development effort by Abbott Laboratories, Taisho Pharmaceuticals, and Advanced Life Sciences, intended to be marketed under the trade name Restanza for the treatment of community-acquired pneumonia.[L14006, A203369]...
Investigational
Matched Iupac: … oxy}-4-ethyl-3a,7,9,11,13,15-hexamethyl-11-{[3-(quinolin-3-yl)prop-2-en-1-yl]oxy}-tetradecahydro-1H-oxacyclotetradeca ... [4,3-d][1,3]oxazole-2,6,8,14-tetrone ... (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl] …
Matched Description: … Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an …

B7-H3-specific chimeric antigen receptor T cells

Investigational

Urtoxazumab

Investigational

BI-836826

Investigational

Zapnometinib

Investigational

GW842166

GW842166X has been used in trials studying the treatment of Pain, Analgesia, Inflammation, Osteoarthritis, and Pain, Inflammatory, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cyclocreatine

Investigational
Matched Synonyms: … 2-imino-1-imidazolidineacetic acid ... 1-carboxymethyl-2-imino-imidazolidine …
Matched Iupac: … 2-(2-iminoimidazolidin-1-yl)acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Detomidine

Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride. This drug is prescribed by veterinarians and is marketed as Dormosedan. Currently, it is only approved by the FDA for use in horses but has been studied for...
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phencyclidine

A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As...
Illicit
Matched Synonyms: … 1-(1-Phenylcyclohexyl)piperidine …
Matched Iupac: … 1-(1-phenylcyclohexyl)piperidine …
Matched Salts cas: … 956-90-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Liposomal prostaglandin E1

Liposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent. The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways that PGE-1 alone could not achieve.
Investigational
Matched Description: … that PGE-1 alone could not achieve. ... The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways …

Tasisulam

Tasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
Investigational
Matched Salts cas: … 519055-63-1 …

Rilotumumab

Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.
Investigational

GSK-2981278

GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis).
Investigational
Matched Synonyms: … Ror gama modulator 1 …
Matched Iupac: … N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-[(oxan-4-yl)methoxy]benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

EDI-200

EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational

Tienilic acid

Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Deoxy-2-fluoro-beta-D-cellotrioside

Experimental
Investigational
Matched Synonyms: … β-D-Glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->4)-2-deoxy-2-fluoro-α-D-glucopyranose …
Matched Iupac: … yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... 3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6S)-6-{[(2R,3S,4S,5R,6S)-5-fluoro-4,6-dihydroxy-2-(hydroxymethyl)oxan-3- …

Dianhydrogalactitol

Dianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
Investigational
Matched Iupac: … (1R,2S)-1-[(2R)-oxiran-2-yl]-2-[(2S)-oxiran-2-yl]ethane-1,2-diol …

SARS-CoV-2 Sclamp

The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp. The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in...
Investigational
Matched Synonyms: … UQ-1-SARS-CoV-2-Sclamp …
Matched Description: … As of July 13, 2020, the candidate is being tested for safety and immunogenicity in Phase 1 clinical ... The SARS-CoV-2 Sclamp Vaccine was developed within 3 weeks and moved immediately into preclinical testing …

Diethyltryptamine

Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
Experimental
Illicit
Matched Synonyms: … 3-(2-Diethylaminoethyl)indole …
Matched Iupac: … diethyl[2-(1H-indol-3-yl)ethyl]amine …
Displaying drugs 4126 - 4150 of 4568 in total