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Displaying drugs 5426 - 5450 of 5601 in total

Vonlerolizumab

Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational

Ecgonine

Experimental
Illicit
Matched Iupac: … (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …

Pradefovir mesylate

Pradefovir mesilate (previously known as MB-06886, Hepavir B and remofovir mesylate) is an orally administered small molecule compound that belongs to a novel series of phosphate and phosphonate prodrugs of adefovir. Adefovir (Hepsera) is an acyclic phosphonate analogue of adenine that is used to treat hepatitis B virus. As adefovir...
Investigational
Matched Iupac: … (2R,4S)-2-{[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}-4-(3-chlorophenyl)-1,3,2lambda5-dioxaphosphinan-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Abacavir hydroxyacetate

Prurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis.
Investigational
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methyl 2-hydroxyacetate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pyronaridine

Pyronaridine has been investigated for the treatment of Malaria.
Investigational
Matched Iupac: … 4-({7-chloro-2-methoxybenzo[b]1,5-naphthyridin-10-yl}amino)-2,6-bis[(pyrrolidin-1-yl)methyl]phenol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Gimatecan

Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational

Buthionine sulfoximine

Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Investigational
Matched Synonyms: … Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)- …
Matched Iupac: … 2-amino-4-[butyl(imino)oxo-lambda6-sulfanyl]butanoic acid …

Setrobuvir

Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
Investigational
Matched Iupac: … N-{3-[(1R,2S,7R,8S)-3-[(4-fluorophenyl)methyl]-6-hydroxy-4-oxo-3-azatricyclo[6.2.1.0^{2,7}]undec-5-en ... -5-yl]-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-7-yl}methanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Radalbuvir

Radalbuvir has been used in trials studying the treatment of Chronic Hepatitis C, Chronic HCV Infection, and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … 5-(3,3-dimethylbut-1-yn-1-yl)-3-{N-[(1s,4s)-4-hydroxy-4-{[(3S)-oxolan-3-yloxy]methyl}cyclohexyl](1R)- ... 4-methylcyclohex-3-ene-1-amido}thiophene-2-carboxylic acid …

PF-06751979

PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).
Investigational
Matched Iupac: … 4-yl}-5-(difluoromethoxy)pyridine-2-carboxamide ... N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4H,4aH,5H,6H,8H,8aH-pyrano[3,4-d][1,3]thiazin-8a-yl]-1,3-thiazol- …

SR 140333

SR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Investigational
Matched Iupac: … 1-{2-[(3R)-3-(3,4-dichlorophenyl)-1-{2-[3-(propan-2-yloxy)phenyl]acetyl}piperidin-3-yl]ethyl}-4-phenyl …

Retagliptin

Retagliptin is under investigation in clinical trial NCT02822534 (The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients).
Investigational
Matched Description: … NCT02822534 (The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 …

Onfekafusp alfa

Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational

Ramatroban

Ramatroban has been used in trials studying the treatment of Asthma.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Evobrutinib

Evobrutinib is under investigation in clinical trial NCT03934502 (Effect of Meal Composition and Timing on Evobrutinib Bioavailability).
Investigational
Matched Iupac: … 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one …

BB-1701

BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed by Bliss Biopharmaceutical.
Investigational

OC-459

OC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.
Investigational
Matched Iupac: … 2-{5-fluoro-2-methyl-3-[(quinolin-2-yl)methyl]-1H-indol-1-yl}acetic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Sorivudine

Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
Investigational
Matched Iupac: … 5-[(E)-2-bromoethenyl]-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …

C-CAR039

C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational

Capromorelin

Capromorelin is under investigation in clinical trial NCT00527046 (Effects Of An Oral Growth Hormone Secretagogue In Older Functionally Limited Adults).
Investigational
Matched Iupac: … N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-2H,3H,3aH,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(benzyloxy ... )-1-oxopropan-2-yl]-2-amino-2-methylpropanamide …

Cimetropium

Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada.
Experimental
Investigational
Matched Iupac: … (1R,2R,4S,5S,7S)-9-(cyclopropylmethyl)-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo …

Guadecitabine

Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Investigational
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydro-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy}({[(2R ... ,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy})phosphinic acid …

Vaniprevir

Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C Virus Infection.
Investigational
Matched Iupac: … (1R,21S,24S)-21-tert-butyl-N-[(1R,2R)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethylcyclopropyl]-16,16-dimethyl …
Matched Salts cas: … 1269195-08-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Batefenterol

Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … 1-(2-{[2-chloro-4-({[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl]amino}methyl)-5 ... -methoxyphenyl]carbamoyl}ethyl)piperidin-4-yl N-{[1,1'-biphenyl]-2-yl}carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic beta-2 Receptor Agonists …

Zoliflodacin

Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Investigational
Matched Iupac: … (4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-5',15'-dioxa-2' …
Displaying drugs 5426 - 5450 of 5601 in total