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Displaying drugs 551 - 575 of 847 in total
Vapitadine is an antihistamine that Barrier Therapeutics is developing as a treatment for allergic reactions of the skin, such as those associated with hives and for the itch associated with atopic dermatitis. An advantage of vapitadine over other antihistamines may be the absence of the sedation, even at high doses.
Investigational
Investigational
Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of...
Investigational
Octenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).
Investigational
Zelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
Investigational
Investigational
Vanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression. Vanoxerine was later evaluated as a potential treatment for cocaine addiction due to its ability to block dopamine reuptake with a slower dissociation rate than cocaine. Although...
Investigational
Investigational
Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.
Investigational
Matched Iupac: … 2,3-dihydro-1lambda6,2-benzothiazole-1,1,3-trione …
Investigational
Matched Iupac: … 2,3-dihydro-1H-isoindole-1,3-dithione …
Experimental
Investigational
Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
Investigational
Matched Iupac: … 2-phenyl-2,3-dihydro-1,2-benzoselenazol-3-one …
Aminorex is an amphetamine-like anorectic agent. It may cause pulmonary hypertension.
Experimental
Illicit
Matched Iupac: … 5-phenyl-4,5-dihydro-1,3-oxazol-2-amine …
Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
Investigational
Matched Iupac: … 5-(aminomethyl)-2,3-dihydro-1,2-oxazol-3-one …
Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational
AQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria.
Investigational
Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
Investigational
Investigational
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Investigational
Investigational
AZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).
Investigational
Matched Iupac: … 2-[(3S)-7-fluoro-4-(3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonyl)-3,4-dihydro-2H-1,4-benzoxazin-3- …
An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, primarily because of its ability to mimic the function of glutathione peroxidase.
Investigational
Matched Iupac: … 4,4-dimethyl-3,4-dihydro-2H-1,2-benzoselenazine …
Investigational
Indantadol has been used in trials studying the treatment of Cough and Diabetic Peripheral Neuropathic Pain.
Investigational
Matched Iupac: … 2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide …
Zamicastat has been used in trials studying the treatment of Hypertension and Chronic Heart Failure.
Investigational
Matched Iupac: … 5-[2-(benzylamino)ethyl]-1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-2,3-dihydro-1H-imidazole …
Displaying drugs 551 - 575 of 847 in total