Displaying drugs 3226 - 3250 of 3283 in total
Cefmenoxime
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically ... used in the treatment of female gynecologic and obstetric infections. ... It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically ... used in the treatment of female gynecologic and obstetric infections. ... It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria …
DPM-1001
Investigational
Matched Synonyms: … Cholan-24-oic acid, 7-hydroxy-3-[[4-[(2-pyridinylmethyl)amino]butyl]amino]-, methyl ester, (3β,5α,7α) …
(7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid
Experimental
Matched Name: … Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
(2S)-({(5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid
Experimental
Matched Name: … (5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid …
Matched Iupac: … [(5-ethylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}-2-(4-fluorophenyl)acetic acid …
Matched Iupac: … [(5-ethylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}-2-(4-fluorophenyl)acetic acid …
[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester
Experimental
Matched Name: … Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid …
2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid
Experimental
Matched Name: … 2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid …
Matched Iupac: … -[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-4-{4'-ethoxy-[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
Matched Iupac: … -[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-4-{4'-ethoxy-[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE
Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL] …
Prasterone sulfate
DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Synonyms: … Androst-5-en-17-on-3beta-yl sulfuric acid …
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid …
Matched Description: … ACTH and prolactin. ... DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ... DHEA sulfate is the major steroid of the fetal adrenal. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid …
Matched Description: … ACTH and prolactin. ... DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ... DHEA sulfate is the major steroid of the fetal adrenal. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Retlirafusp alfa
Investigational
Matched Synonyms: … 136-type II transforming growth factor .beta. receptor (human isoform 1), disulfide with (85-glutamic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pregabalin
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Iupac: … (3S)-3-(aminomethyl)-5-methylhexanoic acid …
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended ... Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … LYRICA 20MG/ML LOE Z EINN ... LYRICA 20 MG/ML LOE Z EINN ... PG-LIN 75 (Pregabalin Capsules 75 mg) …
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended ... Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … LYRICA 20MG/ML LOE Z EINN ... LYRICA 20 MG/ML LOE Z EINN ... PG-LIN 75 (Pregabalin Capsules 75 mg) …
4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID
Experimental
Matched Name: … 7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID …
7-(1,1-Dioxo-1h-Benzo[D]Isothiazol-3-Yloxymethyl)-2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid
Experimental
Matched Name: … 1h-Benzo[D]Isothiazol-3-Yloxymethyl)-2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid …
Matched Iupac: … carboxyformamido)-7-{[(1,1-dioxo-1lambda6,2-benzothiazol-3-yl)oxy]methyl}-4H,5H,7H-thieno[2,3-c]pyran-3-carboxylic acid …
Matched Iupac: … carboxyformamido)-7-{[(1,1-dioxo-1lambda6,2-benzothiazol-3-yl)oxy]methyl}-4H,5H,7H-thieno[2,3-c]pyran-3-carboxylic acid …
Ulviprubart
Investigational
Matched Synonyms: … anti-[Homo sapiens KLRG1(killer cell lectin like receptor G1, MAFA, CLEC15A)], humanized monoclonal antibody …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
{4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
Experimental
Matched Name: … Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid …
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid …
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid …
2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
Experimental
Matched Name: … 2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID …
Matched Iupac: … [4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic acid …
Matched Iupac: … [4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic acid …
Ioflupane F-18
Investigational
Matched Synonyms: … 8-azabicyclo(3.2.1)octane-2-carboxylic acid, 8-(3-(fluoro-18f)propyl)-3-(4-iodophenyl)-, methyl ester …
7-(1-Methyl-1,2,3-Triazol-4-Yl)-6-Formyl-2,7-Dihydro-[1,4]Thiazepine-3-Carboxylic Acid, Brl42715, C6-(N1-Methyl-1,2,3-Triazolylmethylene)Penem
Experimental
Matched Name: … 7-(1-Methyl-1,2,3-Triazol-4-Yl)-6-Formyl-2,7-Dihydro-[1,4]Thiazepine-3-Carboxylic Acid, Brl42715, C6- …
Matched Iupac: … (7S)-6-formyl-7-(1-methyl-1H-1,2,3-triazol-4-yl)-4,7-dihydro-1,4-thiazepine-3-carboxylic acid …
Matched Iupac: … (7S)-6-formyl-7-(1-methyl-1H-1,2,3-triazol-4-yl)-4,7-dihydro-1,4-thiazepine-3-carboxylic acid …
2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3-oxopropyl]phenyl}(carboxycarbonyl)amino]benzoic acid
Experimental
Matched Name: … 3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3-oxopropyl]phenyl}(carboxycarbonyl)amino]benzoic acid …
Matched Iupac: … methoxycarbonyl)phenoxy]butyl}carbamoyl)-2-{[(prop-2-en-1-yloxy)carbonyl]amino}ethyl]phenyl}formamido)benzoic acid …
Matched Iupac: … methoxycarbonyl)phenoxy]butyl}carbamoyl)-2-{[(prop-2-en-1-yloxy)carbonyl]amino}ethyl]phenyl}formamido)benzoic acid …
(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid
Experimental
Matched Name: … (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid …
Matched Iupac: … (5Z)-7-[(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl]hept-5-enoic acid …
Matched Iupac: … (5Z)-7-[(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl]hept-5-enoic acid …
Cefoperazone
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Synonyms: … amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Lenalidomide
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … and toxicities. ... previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and ... exists as a racemic mixture of the active S(-) and R(+) forms. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Carbocyclic ... Carboxylic Acids ... Phthalic Acids …
Matched Products: … LENALIDOMIDE ACINO …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Carbocyclic ... Carboxylic Acids ... Phthalic Acids …
Matched Products: … LENALIDOMIDE ACINO …
4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
Experimental
Matched Name: … Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid …
Matched Iupac: … naphthalen-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl}methyl)phosphonic acid …
Matched Iupac: … naphthalen-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl}methyl)phosphonic acid …
Displaying drugs 3226 - 3250 of 3283 in total