Displaying drugs 776 - 800 of 1167 in total
Azatadine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …
Eszopiclone
Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones.[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity , offering a safer alternative to other drugs used...
Approved
Investigational
Matched Synonyms: … (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine- ... (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine- ... -Piperazinecarobxylic acid,4-methyl-,(5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b] …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Description: … [A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity[A179827], offering a ... Eszopiclone was initially approved by the FDA in 2004.[L6769] ... Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Zopiclone and prodrugs ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Description: … [A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity[A179827], offering a ... Eszopiclone was initially approved by the FDA in 2004.[L6769] ... Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Zopiclone and prodrugs ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Mannitol
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … may be reduced. ... or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative ... (CPD) AND OPTISOL (AS-5) Red Cell Preservative …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Diet, Food, and Nutrition ... Blood Substitutes and Perfusion Solutions …
Matched Products: … B. BRAUN OSMOFUNDIN 20% ... B. BRAUN OSMOFUNDIN 10% (500ML) ... %20 MANNITOL ÇÖZELTISI BFS,150 ML,1 ŞIŞE,SETLI …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative ... (CPD) AND OPTISOL (AS-5) Red Cell Preservative …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Diet, Food, and Nutrition ... Blood Substitutes and Perfusion Solutions …
Matched Products: … B. BRAUN OSMOFUNDIN 20% ... B. BRAUN OSMOFUNDIN 10% (500ML) ... %20 MANNITOL ÇÖZELTISI BFS,150 ML,1 ŞIŞE,SETLI …
Dicloxacillin
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Products: … Truemed Group LLC …
Nedometinib
Investigational
Matched Synonyms: … 2-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-1-methyl-1h-pyrrolo(2,3-b)pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Porcine recombinant factor VIII B-domain truncated ... Antihemophilic factor porcine, B-domain truncated recombinant ... RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... porcine FVIII treatment approved for AHA that allows physicians to manage the treatment's efficacy and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... porcine FVIII treatment approved for AHA that allows physicians to manage the treatment's efficacy and …
Matched Categories: … Blood and Blood Forming Organs …
Vitamin B 12 factor IIIm
Experimental
Matched Synonyms: … Vitamin B 12 factor IIIm ... 5-Methoxybenzimidazole vitamin B12 …
Matched Name: … Vitamin B 12 factor IIIm …
Matched Name: … Vitamin B 12 factor IIIm …
AMG-208
AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Investigational
Matched Synonyms: … 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched International brands: … Bo Shu Te …
Matched Description: … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant ... also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and …
Matched Products: … Truemed Group LLC …
Matched Description: … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant ... also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and …
Matched Products: … Truemed Group LLC …
Rabies virus inactivated antigen, B
Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Name: … Rabies virus inactivated antigen, B …
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins …
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins …
3D-185 free base
Investigational
Matched Synonyms: … Benzamide, N-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo(3,4-B)pyridin-3-yl)-4-(3,3-dimethyl-1- …
SEA-BCMA
Investigational
Matched Synonyms: … Nonfucosylated humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting B-cell maturation antigen …
KITE-222
Investigational
Matched Synonyms: … therapy engineered to express an antibody-derived single-chain variable fragment that recognizes C-type …
Typhoid Vaccine Live
Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.
Approved
Matched Synonyms: … Salmonella typhi Ty21a live antigen ... Typhoid vaccine (salmonella typhi Ty21a) ... Salmonella enterica subsp. enterica serovar typhi …
Matched Description: … typhi* by inducing a local immune response in the intestinal tract. ... It contains the attenuated strain *Salmonella typhi* Ty21a. ... The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by *Salmonella …
Matched Categories: … Inactivated Salmonella Typhi Vaccine ... Live Attenuated Salmonella Typhi Vaccine …
Matched Description: … typhi* by inducing a local immune response in the intestinal tract. ... It contains the attenuated strain *Salmonella typhi* Ty21a. ... The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by *Salmonella …
Matched Categories: … Inactivated Salmonella Typhi Vaccine ... Live Attenuated Salmonella Typhi Vaccine …
Clomipramine
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine …
Matched Description: … Clomipramine may be used to treat obsessive-compulsive disorder and disorders with an obsessive-compulsive ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... , are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Description: … Clomipramine may be used to treat obsessive-compulsive disorder and disorders with an obsessive-compulsive ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... , are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
VidPrevtyn Beta
VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is
derived from Sf9 cells of the fall...
Approved
Investigational
Matched Synonyms: … SARS-CoV-2 prefusion Spike delta TM protein, recombinant (B.1.351 strain) …
Matched Description: … (GSK) and Sanofi Pasteur. ... [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant ... VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline …
Matched Description: … (GSK) and Sanofi Pasteur. ... [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant ... VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline …
P-BCMA-101
P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Investigational
Matched Synonyms: … Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen …
Leflunomide
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … Truemed Group LLC …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … Truemed Group LLC …
beta-Naphthoflavone
β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Experimental
Matched Synonyms: … 3-phenyl-1H-naphtho(2,1-b)pyran-1-one …
Matched Description: … β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and ... induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). ... It may be a chemopreventive agent. …
Matched Description: … β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and ... induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). ... It may be a chemopreventive agent. …
Cannabinol
Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Experimental
Investigational
Matched Synonyms: … 6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol …
Matched Categories: … Cannabinoids and similars …
Matched Categories: … Cannabinoids and similars …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Bms-986089 (fully human anti-myostatin adnectin) ... -986089 fibronectin tenth type iii domain-derived), dimer ... Adnectin, anti-(human growth differentiation factor 8) (synthetic clone prd-1474 fibronectin type iii …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Valziflocept
Investigational
Matched Synonyms: … Human immunoglobulin gamma fc region receptor ii-b (fc.gamma.rii-b), extracellular n-terminal fragment …
Imipramine
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Matched Description: … Imipramine may be used to treat depression and nocturnal enuresis in children [FDA Label]. ... In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. ... and clomipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Description: … Imipramine may be used to treat depression and nocturnal enuresis in children [FDA Label]. ... In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. ... and clomipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup c. The vaccine contains N. meningitis serogroup c capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Name: … Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen …
Matched Description: … The vaccine contains *N. meningitis* serogroup c capsular polysaccharide antigens that are purified and ... intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria ... Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active …
Matched Description: … The vaccine contains *N. meningitis* serogroup c capsular polysaccharide antigens that are purified and ... intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria ... Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active …
Displaying drugs 776 - 800 of 1167 in total