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Displaying drugs 801 - 825 of 841 in total

3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide

Experimental
Matched Name: … 3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl …
Matched Iupac: … 3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Description: … It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be ... Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue ... used instead of other macrolides for some sexually transmitted and enteric infections. …
Matched Categories: … cefixime and azithromycin ... Macrolides, Lincosamides and Streptogramins ... azithromycin, fluconazole and secnidazole …
Matched Products: … AZITHROMYCIN HEXAL 250MG ... AZITHROMYCIN HEXAL 500MG ... Azithromycin "Hexal" 250 mg - Filmtabletten …

(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE

Experimental
Matched Name: … (2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN …
Matched Iupac: … (2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-[(1r,4S)-4-{[1,2,4]triazolo[1,5- …

(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE

Experimental
Matched Name: … (2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1- …
Matched Iupac: … (3R)-3-amino-1-[(8R)-8-methyl-2-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[1,5-a]pyrazin-7-yl]-4-( …

N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE

Experimental
Matched Name: … N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN …
Matched Iupac: … N-{2,2-difluoro-2-[(2R)-piperidin-2-yl]ethyl}-2-{[2-(1H-1,2,4-triazol-1-yl)phenyl]methyl}-[1,3]oxazolo …

Latanoprost

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … Antiglaucoma Preparations and Miotics ... latanoprost and netarsudil …
Matched Products: … LATANOPROST HEXAL ATR …

Domperidone

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DOMPERIDON HEXAL 10MG TABL …

(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE

Experimental
Matched Name: … (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A] …
Matched Iupac: … (2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[(1r,4S)-4-{[1,2,4]triazolo[1,5 …

6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM

Experimental
Matched Name: … -2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO …
Matched Iupac: … (2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-(4-{[1,2,4]triazolo[1,5-a]pyridin …

2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid

Experimental
Matched Name: … 2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid …

Levofloxacin

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Matched Products: … LEVOFLOXACIN HEXAL 250MG ... LEVOFLOXACIN HEXAL 500MG …

Hexetidine

A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.
Approved
Investigational
Matched International brands: … Vagi-Hex …
Matched Iupac: … 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine …
Matched Description: … A bactericidal and fungicidal antiseptic. ... It is used as a 0.1% mouthwash for local infections and oral hygiene. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … VAGI-HEX 10 MG VAJINAL TABLET, 12 ADET …

1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea

Experimental
Matched Name: … 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino …
Matched Iupac: … 3-[5-methyl-2-(trifluoromethyl)furan-3-yl]-1-{5-[2-({6-[(1H-1,2,4-triazol-5-yl)amino]pyrimidin-4-yl}amino …

(2E,4R,5S)-2,3,4,5-TETRAHYDROXY-6-(PALMITOYLOXY)HEX-2-ENOIC ACID

Experimental
Matched Name: … (2E,4R,5S)-2,3,4,5-TETRAHYDROXY-6-(PALMITOYLOXY)HEX-2-ENOIC ACID …

Captopril

Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … CAPTOPRIL E IDROCLOROTIAZIDE HEXAL ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... captopril and diuretics …
Matched Products: … CAPTOPRIL HEXAL …

Nifedipine

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … NIFEDIPINA HEXAL …

Cilastatin

Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …

[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate

Experimental
Matched Name: … [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate …
Matched Iupac: … {[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}(hex-5-en-1-yl)phosphinic acid …

Linezolid

Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most ... generally more effective and tolerable than its predecessor. ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and …
Matched Products: … LINEZOLID HEXAL 600MG …

Cefixime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … , and meningitis. ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … CEFIXIMA HEXAL AG …

2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide

Experimental
Matched Name: … 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide …
Matched Iupac: … 5-(hex-1-yn-1-yl)-N-[(methylcarbamothioyl)amino]furan-2-carboxamide …

[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate

Experimental
Matched Name: … [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate …
Matched Iupac: … {[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}(hex-5-en-1-yl)phosphinic acid …

Atenolol

Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and …
Matched Mixtures name: … ATENOLOLO CLORTALIDONE HEXAL ... ATENOLOLO CLORTALIDONE HEXAL ... Atenolol and Chlorthalidone …
Matched Categories: … atenolol and thiazides ... atenolol and nifedipine ... Beta Blocking Agents and Thiazides ... atenolol and other diuretics ... Beta blocking agents and calcium channel blockers …
Matched Products: … ATENOLOLO HEXAL …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and …
Matched Products: … LEVETIRACETAM HEXAL 250MG ... LEVETIRACETAM HEXAL 500MG ... LEVETIRACETAM HEXAL 750MG …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil …
Matched Products: … VERAPAMIL HEXAL …
Displaying drugs 801 - 825 of 841 in total